Pentanedioic acid, 2,4-diacetyl-3-(3-nitrophenyl)-, dimethyl ester Chemical Properties

Boiling point:

507.7±50.0 °C(Predicted)

Density 

1.280±0.06 g/cm3(Predicted)

pka

9.98±0.59(Predicted)

Pentanedioic acid, 2,4-diacetyl-3-(3-nitrophenyl)-, dimethyl ester Usage And Synthesis

Uses

Dimethyl 2,4-diacetyl-3-(3-nitrophenyl)pentanedioate is an intermediate in the synthesis of Methyl 2-Methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate (M338310), a nicardipine impurity. Also, it is derived from Methyl Acetoacetate (O848425), which is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.