CEP-28122 monomesilate hydrochloride salt
CEP-28122 monomesilate hydrochloride salt Basic information
- Product Name:
- CEP-28122 monomesilate hydrochloride salt
- Synonyms:
-
- CEP-28122 monomesilate hydrochloride salt
- (1S,2S,3R,4R)-3-(5-chloro-2-((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-ylamino)pyrimidin-4-ylamino)bicyclo[2.2.1]hept-5-ene-2-carboxamide methanesulfonate
- CEP-28122 MS SALT
- CEP-28122 Mesylate
- (1S,2S,3R,4R)-3-((5-Chloro-2-(((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide methanesulfonate hydrochloride
- CEP-28122 mesylate hydrochloride
- CAS:
- 1354545-57-5
- MF:
- C29H40Cl2N6O6S
- MW:
- 671.6355
- Mol File:
- 1354545-57-5.mol
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CEP-28122 monomesilate hydrochloride salt Usage And Synthesis
Uses
CEP-28122 mesylate hydrochloride is a diaminopyrimidine derivative.CEP-28122 mesylate hydrochloride is a potent, selective, and orally bioavailable ALK inhibitor with an IC50 of 1.9 nM. CEP-28122 mesylate hydrochloride has antitumor and good pharmacokinetic activity[1].
References
[1] Mangeng Cheng, et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 2012 Mar;11(3):670-9. DOI:10.1158/1535-7163.MCT-11-0776
CEP-28122 monomesilate hydrochloride saltSupplier
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