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MANOOL

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MANOOL Basic information

Product Name:
MANOOL
Synonyms:
  • MANOOL
  • 4AR-TRANS-5-(1,5,5,8AS-TETRAMETHYL-2-METHYLENEDECAHYDRO-1-NAPHTHALENYL)-3-R-METHYL-1-PENTEN-3-OL
  • 1-Naphthalenepropanol, alpha-ethenyldecahydro-alpha,5,5,8a-tetramethyl-2-methylene-, [1S-[1alpha(S*),4abeta,8aalpha]]-
  • 5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol
  • Labda-8(20),14-dien-13-ol, (13R)-
  • 4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR
  • 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, (.alpha.R,1S,4aS,8aS)-
  • 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8A-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4A.beta.,8A.alpha.]]-
CAS:
596-85-0
MF:
C20H34O
MW:
290.48
Product Categories:
  • Miscellaneous Natural Products
Mol File:
596-85-0.mol
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MANOOL Chemical Properties

Melting point:
49-52 °C(lit.)
Boiling point:
150-153 °C(Press: 0.3 Torr)
Density 
0.93±0.1 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
4°C, stored under nitroge
solubility 
Benzene (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Low-Melting Solid
pka
14.47±0.29(Predicted)
color 
White to Off-White
LogP
6.790 (est)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3

MSDS

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MANOOL Usage And Synthesis

Uses

Maintains anti-proliferative activity against human malignant cell strains.

Definition

ChEBI: A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13.

Cytotoxicity

IC50 (μg/mL): 49.3 (V79), 15.6 (B16F10),17.1 (MCF-7), 6.7 (HeLa), 28.5 (HepG2),9.6 (MO59 J), 6.7 (U343), 13.1 (U251)(de Oliveira et al. 2016)

MANOOLSupplier

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