MANOOL
MANOOL Basic information
- Product Name:
- MANOOL
- Synonyms:
-
- MANOOL
- 4AR-TRANS-5-(1,5,5,8AS-TETRAMETHYL-2-METHYLENEDECAHYDRO-1-NAPHTHALENYL)-3-R-METHYL-1-PENTEN-3-OL
- 1-Naphthalenepropanol, alpha-ethenyldecahydro-alpha,5,5,8a-tetramethyl-2-methylene-, [1S-[1alpha(S*),4abeta,8aalpha]]-
- 5-(5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl)-3-methyl-1-penten-3-ol
- Labda-8(20),14-dien-13-ol, (13R)-
- 4ARTRANS-5-(-TETRAME-2-METHYLENEDECAHYDR
- 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, (.alpha.R,1S,4aS,8aS)-
- 1-Naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8A-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4A.beta.,8A.alpha.]]-
- CAS:
- 596-85-0
- MF:
- C20H34O
- MW:
- 290.48
- Product Categories:
-
- Miscellaneous Natural Products
- Mol File:
- 596-85-0.mol
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MANOOL Chemical Properties
- Melting point:
- 49-52 °C(lit.)
- Boiling point:
- 150-153 °C(Press: 0.3 Torr)
- Density
- 0.93±0.1 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- 4°C, stored under nitroge
- solubility
- Benzene (Slightly), Chloroform (Slightly), Methanol (Slightly)
- form
- Low-Melting Solid
- pka
- 14.47±0.29(Predicted)
- color
- White to Off-White
- Specific Gravity
- 0.97
- Odor
- Very delicate, woody, dry-sweet, and extremely tenacious odor
- LogP
- 6.790 (est)
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MSDS
- Language:English Provider:SigmaAldrich
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MANOOL Usage And Synthesis
Uses
Maintains anti-proliferative activity against human malignant cell strains.
Definition
ChEBI: A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13.
Preparation
By extraction of cornrninuted wood of Dacrydium biforme, a tree indigenous to New Zealand, with alcohol or Acetone. The extract is neutralized with alkali, and the crude Manool may be recrystallized.
Cytotoxicity
IC50 (μg/mL): 49.3 (V79), 15.6 (B16F10),17.1 (MCF-7), 6.7 (HeLa), 28.5 (HepG2),9.6 (MO59 J), 6.7 (U343), 13.1 (U251)(de Oliveira et al. 2016)
MANOOLSupplier
J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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HBCChem, Inc.
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- +1-510-219-6317
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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- +86-400-002-6226 +86-13028896684;
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BOC Sciences
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- info@bocsci.com
Hubei xin bonus chemical co. LTD
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- 86-13657291602
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