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(-)-Corey lactone diol

Basic information Safety Supplier Related

(-)-Corey lactone diol Basic information

Product Name:
(-)-Corey lactone diol
Synonyms:
  • (-) COREY LACTONE DIOL
  • (-)-COREY LACTONE DIOL,98%
  • (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,
  • (1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone
  • (1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
  • (3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one
  • (-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one,98%
  • (+)-6β-Hydroxymethyl-7α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
CAS:
32233-40-2
MF:
C8H12O4
MW:
172.18
EINECS:
608-721-8
Product Categories:
  • Latanoprost
  • Prostaglandins
  • API
Mol File:
32233-40-2.mol
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(-)-Corey lactone diol Chemical Properties

Melting point:
117-119 °C(lit.)
Boiling point:
262.49°C (rough estimate)
Density 
1.2104 (rough estimate)
refractive index 
1.4455 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
14.36±0.40(Predicted)
form 
Crystalline Powder or Crystals
color 
White to beige-brown
optical activity
[α]20/D 44°, c = 1.4 in methanol
InChIKey
VYTZWRCSPHQSFX-GBNDHIKLSA-N
CAS DataBase Reference
32233-40-2(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29322090

MSDS

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(-)-Corey lactone diol Usage And Synthesis

Chemical Properties

white to beige-brown cryst. powder or crystals

Uses

(-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia.

Definition

ChEBI: (-)-corey lactone is a gamma-lactone.

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