Basic information Safety Supplier Related

DL-METHIONINE DL-SULFOXIMINE

Basic information Safety Supplier Related

DL-METHIONINE DL-SULFOXIMINE Basic information

Product Name:
DL-METHIONINE DL-SULFOXIMINE
Synonyms:
  • 2-amino-4-(s-methylsulfonimidoyl)-butanoicaci
  • 2-amino-4-(s-methylsulfonimidoyl)butanoicacid
  • dl-methionine-dl-sulfoximin
  • dl-sulfoximin
  • methioninesulfoximine
  • 2-amino-4-(S-methylsulphonimidoyl)butyric acid
  • 2-Amino-4-(S-methylsulfonimidoyl)butyric acid
  • METHIONINESULPHOXIME
CAS:
1982-67-8
MF:
C5H12N2O3S
MW:
180.23
EINECS:
217-845-8
Product Categories:
  • Amino Acids
Mol File:
1982-67-8.mol
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DL-METHIONINE DL-SULFOXIMINE Chemical Properties

Melting point:
214-218 °C (decomp)
Boiling point:
352.2±52.0 °C(Predicted)
Density 
1.215 (estimate)
refractive index 
1.6430 (estimate)
storage temp. 
2-8°C
form 
Solid
color 
White to off-white
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
WS3560000
HS Code 
29252900
Toxicity
mouse,LD50,intraperitoneal,218mg/kg (218mg/kg),Proceedings of the Society for Experimental Biology and Medicine. Vol. 94, Pg. 12, 1957.

MSDS

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DL-METHIONINE DL-SULFOXIMINE Usage And Synthesis

Uses

Methionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase with convulsive effects. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine, which may provide important insights in neurobiological research. Methionine sulfoximine has also been used to study mechanisms related to epilepsy and its inhibitory potential[1].

Definition

ChEBI: A non-proteinogenic alpha-amino acid that is the sulfoximine derivative of methionine .

References

[1] Catalytic cooperativity and subunit interactions in Escherichia coli glutamine synthetase: binding and kinetics with methionine sulfoximine and related inhibitors

DL-METHIONINE DL-SULFOXIMINESupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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Jiangsu Hongmin Pharmaceutical Co., Ltd.
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