Basic information Safety Supplier Related

MET-GLU-HIS-PHE-ARG-TRP-GLY

Basic information Safety Supplier Related

MET-GLU-HIS-PHE-ARG-TRP-GLY Basic information

Product Name:
MET-GLU-HIS-PHE-ARG-TRP-GLY
Synonyms:
  • H-MET-GLU-HIS-PHE-ARG-TRP-GLY-OH
  • ADRENOCORTICOTROPIC HORMONE FRAGMENT 4-10
  • ADRENOCORTICOTROPIC HORMONE (4-10)
  • ADRENOCORTICOTROPIC HORMONE (4-10), HUMAN
  • ADRENOCORTICOTROPIC HORMONE HUMAN FRAGMENT 4-10
  • ACTH (4-10)
  • ACTH (4-10), HUMAN
  • L-MET-GLU-HIS-PHE-ARG-TRP-GLY
CAS:
4037-01-8
MF:
C44H59N13O10S
MW:
962.09
Product Categories:
  • Adrenocorticotropic Hormones (ACTH)
  • Peptides and Proteins
  • Peptides for Cell Biology
  • Peptide
Mol File:
4037-01-8.mol
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MET-GLU-HIS-PHE-ARG-TRP-GLY Chemical Properties

Density 
1.48±0.1 g/cm3(Predicted)
RTECS 
MC0596950
storage temp. 
−20°C
pka
3.32±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
Met-Glu-His-Phe-Arg-Trp-Gly
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Safety Information

WGK Germany 
3

MSDS

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MET-GLU-HIS-PHE-ARG-TRP-GLY Usage And Synthesis

Uses

Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist.

Biological Activity

Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 4 receptor (MC4R) agonist.

in vitro

Adrenocorticotropic Hormone (ACTH) (4-10), human (ACTH (4-10)) is the core sequence of all melanocortins and binds selectively to MC4-R. In humans, ACTH (4-10) enters the cerebral fluid compartment after intranasal application and leads to a decrease in total body fat after 6 weeks of continuous treatment.

target

Melanocortin 4 receptor

IC 50

MC4R

References

[1] Wellh?ner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8. DOI:10.1038/ijo.2011.105

MET-GLU-HIS-PHE-ARG-TRP-GLYSupplier

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