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Polypeptide

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Peptide refers to a compound made from the dehydration and further condensation of two or more amino acids. The simplest peptide is composed of two amino acids, called di-peptide. Peptide consisting of multiple amino acids is called polypeptide. Polypeptide consisting of more than 50 amino acids is usually referred to as protein. Peptide is widely distributed in animals, plants and micro-organisms and has important physiological roles. It have various specific effects on growth and development, cell differentiation, brain activity, tumor diseases, immune defense, reproduction control, and anti-aging and other aspects of biological activity. For example, the glutathione is the coenzyme of certain enzymes, playing an important role in the redox processes in vivo. Many kinds of hormones belong to the polypeptide such as oxytocin, vasopressin, glucagon, and adrenocorticotropic hormone. They can regulate the body's metabolism. The hormone regulatory factors secreted by the hypothalamus adjustment factor are also polypeptides. They control the secretion of hormone by other kinds of endocrine glands. In recent years, it has found that the enkephalin (a pentapeptide) in the brain of higher animals has analgesic effect. Many antibiotics produced by microorganisms such as polymyxin, gramicidin, etc. are all peptides with a strong antibacterial effect.

Polypeptide refers to a long chain consisting of a number of amino acid units connected with each other by peptide bonds. There is no strict boundary between the definition of peptides and proteins. We generally refer to a polypeptide comprising only dozens or fewer amino acid units as peptides while referring to the polypeptide containing lot of amino acid units as protein. We often call the amino acid unit contained in polypeptide amino acid residue because these units connected to each other have lost part of the molecule, rather than being as the intact amino acid. Only amino acid residues at both ends of the peptide chain contain free α- amino group or a free α- carboxyl group. The terminal amino acid residue containing free α- amino-terminal residues is called amino group terminal (or N-terminal) residue while the terminal residue containing freedom α- carboxyl- is called the carboxy terminus (or C-terminal) residue. The naming of the polypeptide is according to the order form N terminal residues to C-terminal residues. We also use this order for writing.
For example, the pentapeptide Ser • Gly • Try • Ala • Leu consists of five amino acid residues and four peptide linkages, called glycyl-seryl-tyrosyl-alanyl-leucine. Peptide is widely found in plant and animal tissues with a number of peptides in vivo having special features, collectively known bioactive peptides.

In recent years, it has been found that: almost all the major theories of life sciences, such as immune defense, reproduction control, tumor lesions, and anti-aging all have related bioactive peptides. These theoretical issues are all closely related to the clinical practice, thus the biologically active peptide is also important in practical applications. There are many kinds of bioactive peptides. For example, the adrenocorticotropic hormone that can stimulate the development of adrenal cortex is a kind of 39 peptides; the oxytocin that can cause the contraction of the uterus belongs to nonapeptide; the two kinds of enkephalins having morphine activity are both pentapeptides. Many kinds of antibiotics are also peptides. Another example is the growth factor that is controlled by genes, playing regulatory and controlling effect in cell development. This kind of important material also belongs to polypeptide. Epidermal growth factor contains 50 amino acid residues; the nerve growth factor contains 118 amino acid residues.

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Structure:
Chemical Name:
Secretin
CAS:
17034-35-4
MF:
C130H220N44O41
Structure:
Chemical Name:
D-Camphorsulfonic acid
CAS:
3144-16-9
MF:
C10H16O4S
Structure:
Chemical Name:
Eptifibatide
CAS:
188627-80-7
MF:
C35H49N11O9S2
Structure:
Chemical Name:
L(-)-10-Camphorsulfonyl chloride
CAS:
39262-22-1
MF:
C10H15ClO3S
Structure:
Chemical Name:
Pralmorelin
CAS:
158861-67-7
MF:
C45H55N9O6
Structure:
Chemical Name:
Deslorelin
CAS:
57773-65-6
MF:
C64H83N17O12
Structure:
Chemical Name:
(R)-(-)-4-BENZYL-3-PROPIONYL-2-OXAZOLIDINONE
CAS:
131685-53-5
MF:
C13H15NO3
Structure:
Chemical Name:
Hexarelin
CAS:
140703-51-1
MF:
C47H58N12O6
Structure:
Chemical Name:
Azilsartan
CAS:
147403-03-0
MF:
C25H20N4O5
Structure:
Chemical Name:
Octreotide acetate
CAS:
83150-76-9
MF:
C49H66N10O10S2
Structure:
Chemical Name:
(R)-(+)-1,1'-Bi-2-naphthol
CAS:
18531-94-7
MF:
C20H14O2
Structure:
Chemical Name:
(S)-(+)-4-Phenyl-2-oxazolidinone
CAS:
99395-88-7
MF:
C9H9NO2
Structure:
Chemical Name:
(S)-4-Benzyl-2-oxazolidinone
CAS:
90719-32-7
MF:
C10H11NO2
Structure:
Chemical Name:
(S)-(+)-4-Isopropyl-3-propionyl-2-oxazolidinone
CAS:
77877-19-1
MF:
C9H15NO3
Structure:
Chemical Name:
(4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
CAS:
101711-78-8
MF:
C13H15NO3
Structure:
Chemical Name:
(S)-(-)-1,1'-Bi-2-naphthol
CAS:
18531-99-2
MF:
C20H14O2
Structure:
Chemical Name:
Enfuvirtide
CAS:
159519-65-0
MF:
C204H301N51O64
Structure:
Chemical Name:
Sincalide
CAS:
25126-32-3
MF:
C49H62N10O16S3
Structure:
Chemical Name:
H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT
CAS:
23815-87-4
MF:
C35H52N10O9
Structure:
Chemical Name:
(N-ACETYL)-(4R)-BENZYL-2-OXAZOLIDINONE
CAS:
132836-66-9
MF:
C12H13NO3
Structure:
Chemical Name:
ANGIOTENSIN II, HUMAN
CAS:
4474-91-3
MF:
C50H71N13O12
Structure:
Chemical Name:
GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN
CAS:
107444-51-9
MF:
C149H226N40O45
Structure:
Chemical Name:
ALPHA-MSH
CAS:
581-05-5
MF:
C77H109N21O19S
Structure:
Chemical Name:
NS-398
CAS:
123653-11-2
MF:
C13H18N2O5S
Chemical Name:
CRF (HUMAN, RAT)
CAS:
86784-80-7
MF:
C208H344N60O63S2
Structure:
Chemical Name:
beta-Amyloid (1-42) human
CAS:
107761-42-2
MF:
C203H311N55O60S1
Structure:
Chemical Name:
Bombesin
CAS:
31362-50-2
MF:
C71H110N24O18S
Structure:
Chemical Name:
Ziconotide acetate
CAS:
107452-89-1
MF:
C102H172N36O32S7
Structure:
Chemical Name:
H-TYR-GLY-GLY-PHE-MET-OH
CAS:
58569-55-4
MF:
C27H35N5O7S
Structure:
Chemical Name:
Melanotan-1
CAS:
75921-69-6
MF:
C78H111N21O19
Structure:
Chemical Name:
Pramlintide acetate
CAS:
196078-30-5
MF:
C173H273N51O56S2
Structure:
Chemical Name:
ENDOTHELIN 1 HUMAN, PORCINE
CAS:
117399-94-7
MF:
C109H159N25O32S5
Structure:
Chemical Name:
Exenatide acetate
CAS:
141732-76-5
MF:
C186H286N50O62S
Structure:
Chemical Name:
(R)-DI-2-NAPHTHYLPROLINOL
CAS:
130798-48-0
MF:
C25H23NO
Structure:
Chemical Name:
Dynorphin A (1-13)
CAS:
72957-38-1
MF:
C75H126N24O15
Chemical Name:
ALBUMIN, BOVINE
CAS:
68551-06-4
Structure:
Chemical Name:
AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE
CAS:
131602-53-4
MF:
C45H81N13O14S
Structure:
Chemical Name:
Eptifibatide
CAS:
148031-34-9
MF:
C35H49N11O9S2
Structure:
Chemical Name:
Thymopentin
CAS:
69558-55-0
MF:
C30H49N9O9
Structure:
Chemical Name:
Atosiban
CAS:
90779-69-4
MF:
C43H67N11O12S2
Structure:
Chemical Name:
Antide
CAS:
112568-12-4
MF:
C82H108ClN17O14
Structure:
Chemical Name:
Felypressin
CAS:
56-59-7
MF:
C46H65N13O11S2
Structure:
Chemical Name:
Exendin-4
CAS:
141758-74-9
MF:
C184H282N50O60S
Structure:
Chemical Name:
(R)-4-Benzyl-2-oxazolidinone
CAS:
102029-44-7
MF:
C10H11NO2
Structure:
Chemical Name:
Eledoisin
CAS:
69-25-0
MF:
C54H85N13O15S
Structure:
Chemical Name:
(R)-(-)-3-PROPIONYL-4-ISOPROPYL-2-OXAZOLIDINONE
CAS:
89028-40-0
MF:
C9H15NO3
Structure:
Chemical Name:
(4S)-(-)-4-Isopropyl-2-oxazolidinone
CAS:
17016-83-0
MF:
C6H11NO2
Structure:
Chemical Name:
Growth hormone releasing peptide
CAS:
87616-84-0
MF:
C46H56N12O6
Structure:
Chemical Name:
Histrelin
CAS:
76712-82-8
MF:
C66H86N18O12
Structure:
Chemical Name:
Nesiritide acetate
CAS:
114471-18-0
MF:
C143H244N50O42S4
Structure:
Chemical Name:
(R)-(-)-4-Phenyl-2-oxazolidinone
CAS:
90319-52-1
MF:
C9H9NO2
Structure:
Chemical Name:
VIP
CAS:
40077-57-4
MF:
C147H238N44O42S
Structure:
Chemical Name:
Bivalirudin
CAS:
128270-60-0
MF:
C98H138N24O33
Structure:
Chemical Name:
(R)-(+)-4-Isopropyl-2-oxazolidinone
CAS:
95530-58-8
MF:
C6H11NO2
Structure:
Chemical Name:
Exendin-3 (9-39) amide
CAS:
133514-43-9
MF:
C149H234N40O47S
Structure:
Chemical Name:
FERTIRELIN
CAS:
38234-21-8
MF:
C55H76N16O12
Structure:
Chemical Name:
BETA-MSH, HUMAN
CAS:
17908-57-5
MF:
C118H174N34O35S
Structure:
Chemical Name:
FORMOTHION
CAS:
2540-82-1
MF:
C6H12NO4PS2
Chemical Name:
CHARYBDOTOXIN
CAS:
95751-30-7
MF:
C176H277N57O55S7
Structure:
Chemical Name:
AC-DEVD-AMC
CAS:
169332-61-0
MF:
C30H37N5O13
Structure:
Chemical Name:
GHRELIN (RAT)
CAS:
258338-12-4
MF:
C147H245N45O42
Structure:
Chemical Name:
D-Cyclohexylalaninol
CAS:
205445-49-4
MF:
C9H19NO
Structure:
Chemical Name:
CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2
CAS:
113-80-4
MF:
C43H67N15O12S2
Structure:
Chemical Name:
Angiotensin acetate
CAS:
20071-00-5
MF:
C51H74N14O13
Structure:
Chemical Name:
OREXIN B (HUMAN)
CAS:
205640-91-1
MF:
C123H212N44O35S
Structure:
Chemical Name:
CAERULEIN
CAS:
17650-98-5
MF:
C58H73N13O21S2
Structure:
Chemical Name:
Taltirelin
CAS:
103300-74-9
MF:
C17H23N7O5
Structure:
Chemical Name:
(4S,5R)-(-)-4-METHYL-5-PHENYL-2-OXAZOLIDINONE
CAS:
16251-45-9
MF:
C10H11NO2
Structure:
Chemical Name:
GALANIN, PORCINE
CAS:
88813-36-9
MF:
C146H213N43O40
Structure:
Chemical Name:
GRF (1-44) (HUMAN)
CAS:
83930-13-6
MF:
C215H358N72O66S
Structure:
Chemical Name:
Seractide
CAS:
12279-41-3
MF:
C207H308N56O58S1
Structure:
Chemical Name:
H-ILE-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-ASN-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2
CAS:
123583-37-9
MF:
C180H278N53O54R
Structure:
Chemical Name:
Leupeptin
CAS:
103476-89-7
MF:
C20H38N6O4
Structure:
Chemical Name:
NEUROKININ A
CAS:
86933-74-6
MF:
C50H80N14O14S
Structure:
Chemical Name:
AMYLOID BETA-PROTEIN (HUMAN, 1-40) TRIFLUOROACETATE
CAS:
131438-79-4
MF:
C194H295N53O58S
Structure:
Chemical Name:
AC-YVAD-CHO
CAS:
143313-51-3
MF:
C23H32N4O8
Structure:
Chemical Name:
MASTOPARAN
CAS:
72093-21-1
MF:
C70H131N19O15
Structure:
Chemical Name:
SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE
CAS:
137339-65-2
MF:
C81H118N20O23
Structure:
Chemical Name:
MELITTIN
CAS:
20449-79-0
MF:
C131H229N39O31
Structure:
Chemical Name:
Thymosin beta 4 acetate
CAS:
77591-33-4
MF:
C212H350N56O78S
Structure:
Chemical Name:
NEUROTENSIN
CAS:
55508-42-4
MF:
C78H121N21O20
Structure:
Chemical Name:
BPP 9A
CAS:
35115-60-7
MF:
C53H76N14O12
Chemical Name:
Trypsin inhibitor
CAS:
9035-81-8
MF:
NULL
Structure:
Chemical Name:
ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLN-VAL
CAS:
128315-56-0
MF:
C105H160N30O26S4
Structure:
Chemical Name:
(4R,5S)-(+)-4-METHYL-5-PHENYL-2-OXAZOLIDINONE
CAS:
77943-39-6
MF:
C10H11NO2
Structure:
Chemical Name:
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
CAS:
123562-20-9
MF:
C115H160N26O32S4
Chemical Name:
H-HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2
CAS:
137061-48-4
MF:
C203H331N63O53S1
Structure:
Chemical Name:
PEPTIDE YY, HUMAN
CAS:
118997-30-1
MF:
C194H295N55O57
Structure:
Chemical Name:
AMYLIN, HUMAN
CAS:
122384-88-7
MF:
C8H17O3*
Structure:
Chemical Name:
H-HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-NH2
CAS:
127317-03-7
MF:
C142H224N40O39S
Structure:
Chemical Name:
TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2
CAS:
80448-90-4
MF:
C99H155N31O23
Structure:
Chemical Name:
NOCICEPTIN
MF:
C79H129N27O22
Structure:
Chemical Name:
AC-DEVD-AFC
CAS:
201608-14-2
MF:
C30H34F3N5O13
Structure:
Chemical Name:
ALPHA-CGRP (8-37) (HUMAN)
CAS:
119911-68-1
MF:
C139H230N44O38
Structure:
Chemical Name:
(LEU31,PRO34)-NEUROPEPTIDE Y (PORCINE)
CAS:
125580-28-1
MF:
C190H286N54O56
Structure:
Chemical Name:
OMEGA-CONOTOXIN GVIA
CAS:
106375-28-4
MF:
C120H182N38O43S6
Chemical Name:
PROTAMINE SULFATE
CAS:
9009-65-8
MF:
H2O4S
Structure:
Chemical Name:
X-GAL
CAS:
72122-63-5
MF:
C30H37N5O7
Structure:
Chemical Name:
NEUROKININ B
CAS:
86933-75-7
MF:
C55H79N13O14S2
Structure:
Chemical Name:
(S)-(-)-ALPHA,ALPHA-DI(2-NAPHTHYL)-2-PYRROLIDINEMETHANOL
CAS:
127986-84-9
MF:
C25H23NO