(R)-(+)-1,1'-Bi-2-naphthol
(R)-(+)-1,1'-Bi-2-naphthol Basic information
- Product Name:
- (R)-(+)-1,1'-Bi-2-naphthol
- Synonyms:
-
- (R)-(+)-BI-2-NAPHTHOL
- (R)-[1,1']-Binaphth-2-ol, (R)-BINOL
- (+)-2,2μ-Dihydroxy-1,1μ-dinaphthyl, (R)-(+)-1,1μ-Binaphthalene-2,2μ-diol, (R)-BINOL
- (R)-(+)-1,1'-Bi-2-naphthol 99%
- [aR,(+)]-1,1'-Binaphthalene-2,2'-diol
- [aR,(+)]-Dinaphthol
- R-(+)-1_Bi-2-naphthol
- (R)-(+)-1,1'-Bi-2-na
- CAS:
- 18531-94-7
- MF:
- C20H14O2
- MW:
- 286.32
- EINECS:
- 606-048-4
- Product Categories:
-
- BINOL Series
- Chiral Oxygen
- Intermediates of Dyes and Pigments
- Alcohols and Derivatives
- chiral
- Chiral Reagent
- CHIRAL COMPOUNDS
- Asymmetric Synthesis
- Synthetic Organic Chemistry
- Chiral Compound
- Peptide
- Mol File:
- 18531-94-7.mol
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(R)-(+)-1,1'-Bi-2-naphthol Chemical Properties
- Melting point:
- 215-218 °C
- alpha
- 35.5 º (c=1, THF)
- Boiling point:
- 388.69°C (rough estimate)
- Density
- 1.301
- refractive index
- 36.0 ° (C=1, THF)
- storage temp.
- Store below +30°C.
- solubility
- dioxane: 50 mg/mL, clear
- form
- Powder
- pka
- 8.29±0.50(Predicted)
- color
- white to off-white
- optical activity
- [α]21/D +34°, c = 1 in THF
- Water Solubility
- Insoluble in water. Solubility in THF within almost transparency). Soluble in dioxane 50 mg/mL.
- Merck
- 14,1226
- BRN
- 3616837
- CAS DataBase Reference
- 18531-94-7(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- T,Xi
- Risk Statements
- 25-36-36/37/38
- Safety Statements
- 26-45-24/25-36
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- DU3106100
- F
- 10
- TSCA
- No
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29071590
- Toxicity
- LD50 orally in Rabbit: 113 mg/kg
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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(R)-(+)-1,1'-Bi-2-naphthol Usage And Synthesis
Chemical Properties
white to light yellow crystal powde
Uses
Chiral binapthol imminium salt precursor. Salts were used for an asymmetric epoxidation of olefins.
Definition
ChEBI: (S)-(-)-1,1'-Bi-2-naphthol is a member of naphthols.
Purification Methods
Dissolve it in cold 2.5N NaOH, extract with CH2Cl2, and acidify with 5% HCl. Collect the white precipitate and recrystallise it from aqueous EtOH and dry it in a vacuum [Akimoto & Yamada Tetrahedron 27 5999 1971]. It is optically stable in dioxane-water (100o/24hours). Racemisation: 72% in 1.2N HCl at 100o/24hours and 68% in 0.67M KOH in BuOH at 118o/23hours [Kyba et al. J Am Chem Soc 95 2693 1973]. It has also been crystallised from *C6H6 (solubility is 1%) using Norite or aqueous EtOH after chromatography through silica gel, eluting with Me2CO/*C6H6. [Kyba et al. J Org Chem 42 4173 1977; see also Brussee & Jansen Tetrahedron Lett 24 3261 1983, Akimoto & Yamada Tetrahedron 27 5999 1971, Beilstein 6 IV 7020.]
(R)-(+)-1,1'-Bi-2-naphthol Preparation Products And Raw materials
Preparation Products
(3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL(S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL(R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl(R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol
Raw materials
(R)-(+)-1,1'-Bi-2-naphtholSupplier
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J & K SCIENTIFIC LTD.
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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- 4006608290; 18621169109
- market03@meryer.com
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(R)-(+)-1,1'-Bi-2-naphthol(18531-94-7)Related Product Information
- p-Naphtholbenzein
- Phenmedipham
- Terbinafine hydrochloride
- 1-Naphthol
- (n)-1,1'-bi(2-naphthol),(±)-1,1'-Bi(2-naphthol),99%,(+/-)-1,1'-BI(2-NAPHTHOL),(+/-)-1,1A-Bi-2-naphthol
- 2-Naphthol
- ALPHA-NAPHTHOLBENZEIN
- (S)-(-)-1,1'-Bi-2-naphthol,S-(-)-1,1'-Bi-2-naphthol,99%(S)-BINOL,(S)-1,1 -BI-2-NAPHTHOL ***REVERSE***,(S)-(−)-1,1'-Bi(2-naphthol)
- (R)-(+)-2,2'-DIMETHOXY-1,1'-BINAPHTHYL
- (S)-(+)-6'-DIBROMO-1,1'-BI-2-NAPHTHOL,6,6''-DIBROMO-1,1''-BI-2-NAPHTHOL 95+%,racemic-6,6'-Dibromo-1,1'-bi-2-naphthol,min.98%
- (S)-2'-Methoxy-[1,1']binaphthalenyl-2-ol
- 1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate
- (R)-(-)-1,1'-Binaphthol-2,2'-bis(trifluoromethanesulfonate)
- (R)-(+)-3,3'-Dibromo-1,1'-bi-2-naphthol,99%
- (S)-(+)-1,1'-Bi-2-naphthyl ditosylate
- (-1,1'-Bi-2-Naphthol Deacetate
- (S)-1,1μ-Binaphthalene-2,2μ-diyl bis(trifluoromethanesulfonate), (S)-1,1μ-Bi(2-naphthol) bis(trifluoromethanesulfonate)
- (R)-1,1'-BI-2-NAPHTHOL DIBENZOATE