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N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate

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N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate Basic information

Product Name:
N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate
Synonyms:
  • 2-SUCCINIMIDO-1,1,3,3-TETRAMETHYLURONIM HEXAFLUOROPHOSPHATE
  • 2-SUCCINIMIDO-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE
  • HSTU
  • O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium hexafluorophosphate
  • O-(N-SUCCINIMIDYL)-N,N,N',N'-TETRA-
  • O-(N-Succinimidyl)-N,N,N',N'-tetramethyluroniumhe
  • o-(n-succinimidyl)-n,n,n',n'-tetra-methyluroniumpf6
  • HSTU O-(N-SUCCINIMIDYL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE
CAS:
265651-18-1
MF:
C9H16F6N3O3P
MW:
359.21
Product Categories:
  • Coupling Reagent
Mol File:
265651-18-1.mol
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N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate Chemical Properties

Melting point:
218-221°C
storage temp. 
-20°C
solubility 
Soluble in acetonitrile 0.5 g/mL.
form 
Powder or Crystalline Powder
color 
White to off-white
Sensitive 
Moisture Sensitive
InChIKey
STWZCCVNXFLDDD-UHFFFAOYSA-N
CAS DataBase Reference
265651-18-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-60-37
WGK Germany 
3
HS Code 
29280000
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N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate Usage And Synthesis

Chemical Properties

White to off-white crystalline powder

Uses

Coupling reagent for peptide synthesis and the formation of other amides. Yield in aqueous solution is excellent too.

Uses

Coupling reagent for peptide synthesis and the formation of other amides. Reactant for synthesis of liposomal contrast agents for magnetic resonance imaging, synthesis of protein labeling molecules, synthesis of thiol-reactive Cy5 derivatives.

General Description

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate can be used to prepare N-succinimidyl 4-[18F]fluorobenzoate ([18F]-SFB), a prosthetic group for the fluorination of biomolecules for PET imaging.

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