5-CHLORO-8-NITROQUINOLINE Chemical Properties

Melting point:

136-136.5℃

Boiling point:

353.6±27.0 °C(Predicted)

Density 

1.484±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

pka

0.12±0.29(Predicted)

Appearance

Light yellow to yellow Solid

InChI

InChI=1S/C9H5ClN2O2/c10-7-3-4-8(12(13)14)9-6(7)2-1-5-11-9/h1-5H

InChIKey

DHRPLGHWWKFRKY-UHFFFAOYSA-N

SMILES

N1C2C(=C(Cl)C=CC=2[N+]([O-])=O)C=CC=1

5-CHLORO-8-NITROQUINOLINE Usage And Synthesis

Uses

5-Chloro-8-nitroquinoline itself is not typically used as a final product; its core value lies in its role as a pharmaceutical intermediate. Its primary use is in the synthesis of bioactive molecules, particularly antimalarial drugs.

Reactions

5-Chloro-8-nitroquinoline is a heterocyclic compound featuring a quinoline backbone substituted with a chlorine atom at position 5 and a nitro group at position 8 . The chlorine substituent enhances its biological activity by modulating electronic properties and binding interactions, while the nitro group contributes to its redox activity and coordination chemistry.

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