7-METHYL-6-THIOGUANOSINE Chemical Properties

Melting point:

>175°C (dec.)

storage temp. 

-20°C Freezer, Under Inert Atmosphere

solubility 

DMF: 50 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml

form 

A crystalline solid

color 

White to yellow

Stability:

Air sensitive, Light sensitive, Temperature sensitive

7-METHYL-6-THIOGUANOSINE Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

7-Methyl-6-thioguanosine (MESG) is a chromophoric substrate which can be used for the quantitation of inorganic phosphate. 7-Methyl-6-thioguanosine is also used to determine the activity of purine nucleoside phosphorylase[1][2].

References

[1] Cheng Q, et al. A continuous spectrophotometric assay for protein phosphatases. Anal Biochem. 1995 Mar 20;226(1):68-73. DOI:10.1006/abio.1995.1192
[2] Anna-Maja Aberg, et al. Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue. Scand J Clin Lab Invest. 2010 Feb;70(1):8-14. DOI:10.3109/00365510903359229

7-METHYL-6-THIOGUANOSINE(55727-10-1)Related Product Information

• 7,8-Dihydro-7-methylguanosine
• 7-Methyl-8-thioguanosine
• 1-METHYL-6-THIOGUANOSINE
• 6-Thioguanine
• 7-METHYL-6-MERCAPTOPURINE
• 7-METHYL-6-THIOGUANOSINE
• 6-THIOGUANOSINE