7-METHYL-6-MERCAPTOPURINE
7-METHYL-6-MERCAPTOPURINE Basic information
- Product Name:
- 7-METHYL-6-MERCAPTOPURINE
- Synonyms:
-
- 7-METHYL-6-MERCAPTOPURINE
- METHYL-6-MERCAPTOPURINE, 7-
- 7-Methylpurine-6-thione
- 1,7-Dihydro-7-methyl-6H-purine-6-thione
- METHYL-6-MERCAPTOPURINE, 7-(RG)(CALL)
- 6H-Purine-6-thione, 1,7-dihydro-7-methyl-
- 6-Mercapto-7-methylpurine
- 7-Methyl-6-thiopurine
- CAS:
- 3324-79-6
- MF:
- C6H6N4S
- MW:
- 166.2
- Mol File:
- 3324-79-6.mol
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7-METHYL-6-MERCAPTOPURINE Chemical Properties
- solubility
- DMSO: Soluble
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7-METHYL-6-MERCAPTOPURINE Usage And Synthesis
Uses
7-Methyl-6-mercaptopurine (Compound 4) is a purine derivative and a substrate for thiopurine methyltransferase (TPMT) with Km and Vmax values of 231 μM and 2340 U/mg protein, respectively[1].
References
[1] Deininger M, et al. Purine substrates for human thiopurine methyltransferase. Biochem Pharmacol. 1994;48(11):2135-2138. DOI:10.1016/0006-2952(94)90515-0
[2] P. M. KOCHERGIN V S K E Aleksandrova. Chemical transformations of 6-[(1-methyl-4-nitro-5-imidazolyl)-thio]purine (azathioprine)[J]. Chemistry of Heterocyclic Compounds, 2000, 36 1: 311-318. DOI: 10.1007/bf02256869
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