HUMAN PDGF R-BETA/FC CHIMERA Chemical Properties

storage temp. 

−20°C

solubility 

soluble || water: soluble

form 

buffered aqueous solution

biological source

rabbit

Water Solubility 

soluble
water: soluble

Specific Activity

16-22nmol/min·mg

Safety Information

Hazard Codes 

T

Risk Statements 

61

Safety Statements 

53-45

WGK Germany 

3

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Eye Irrit. 2
Repr. 1B
Skin Irrit. 2

MSDS

• Language:English Provider:SigmaAldrich

HUMAN PDGF R-BETA/FC CHIMERA Usage And Synthesis

Uses

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Biological Activity

The PDGFβ receptor is involved in the development of the kidney, heart, placenta, blood vessels, and cardiovascular system. It also helps to regulate interstitial fluid pressure in tissues thus preventing edema. The activation of the PDGFβ receptor plays a crucial role in the process of wound healing. In addition to these functions, its overexpression is related to gastric cancer.