6-BN-CAMP SODIUM SALT
6-BN-CAMP SODIUM SALT Basic information
- Product Name:
- 6-BN-CAMP SODIUM SALT
- Synonyms:
-
- N6-BENZYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- 6-BN-CAMP, NA
- 6-BN-CAMP SODIUM SALT
- ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6-BENZYL-, SODIUM SALT
- n(6)-benzyl-cyclicadenosine5’-monophosphate
- n6-benzyladenosine-3’,5’-cyclicmonophosphate(6-bn-camp),sodiumsalt
- Adenosine, N-(phenylmethyl)-, cyclic 3',5'-(hydrogen phosphate)
- 6-Bn-cAMP
- CAS:
- 32115-08-5
- MF:
- C17H18N5O6P
- MW:
- 419.33
- Mol File:
- 32115-08-5.mol
More
Less
6-BN-CAMP SODIUM SALT Chemical Properties
- Boiling point:
- 719.8±70.0 °C(Predicted)
- Density
- 1.86±0.1 g/cm3(Predicted)
- pka
- 1.00±0.60(Predicted)
More
Less
6-BN-CAMP SODIUM SALT Usage And Synthesis
Uses
6-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinase (PKA) which does not activate Epac. 6-Bn-cAMP increases hydrolytic stability against PDE, esterases, amidases and considerably higher membrane permeability compared to cAMP[1].
References
[1] Pepe S, et al. Effects of 8-chloroadenosine 3',5'-monophosphate and N6-benzyl-cyclic adenosine 5'-monophosphate on cell cycle kinetics of HL-60 leukemia cells. Cancer Res. 1991 Dec 1;51(23 Pt 1):6263-7. PMID:1657383