8-Benzyloxy-3'-deoxy-3'-fluoroguanosine
8-Benzyloxy-3'-deoxy-3'-fluoroguanosine Basic information
- Product Name:
- 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine
- Synonyms:
-
- 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine
- 8-Benzyloxy-3’-deoxy-3’-fluoroguanosine
- 2-amino-8-(benzyloxy)-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
- CAS:
- 2389988-61-6
- MF:
- C17H18FN5O5
- MW:
- 391.36
- Mol File:
- 2389988-61-6.mol
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8-Benzyloxy-3'-deoxy-3'-fluoroguanosine Chemical Properties
- Boiling point:
- 735.9±70.0 °C(Predicted)
- Density
- 1.76±0.1 g/cm3(Predicted)
- pka
- 12.40±0.70(Predicted)
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8-Benzyloxy-3'-deoxy-3'-fluoroguanosine Usage And Synthesis
Uses
8-Benzyloxy-3’-deoxy-3’-fluoroguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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