8-Benzyloxy-3’-deoxyguanosine Chemical Properties

Boiling point:

734.2±70.0 °C(Predicted)

Density 

1.70±0.1 g/cm3(Predicted)

pka

13.59±0.60(Predicted)

8-Benzyloxy-3’-deoxyguanosine Usage And Synthesis

Uses

8-Benzyloxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

8-Benzyloxy-3’-deoxyguanosine(2389988-57-0)Related Product Information

• 8-Benzyloxy-2'-deoxy-D-guanosine
• 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine