N6-Furfuryl-2'-C-methyladenosine
N6-Furfuryl-2'-C-methyladenosine Basic information
- Product Name:
- N6-Furfuryl-2'-C-methyladenosine
- Synonyms:
-
- N6-Furfuryl-2'-C-methyladenosine
- N6-(2-furanylmethyl)-9H-(3-C-methyl-β-D-ribofuranosyl)adenine
- Adenosine, N-(2-furanylmethyl)-3'-C-methyl-
- N6-Furfuryl-2’-C-methyladenosine
- (2R,3S,4R,5R)-5-(6-((furan-2-ylmethyl)amino)-9H-purin-9-yl)-2-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol
- CAS:
- 1042976-44-2
- MF:
- C16H19N5O5
- MW:
- 361.35
- Mol File:
- 1042976-44-2.mol
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N6-Furfuryl-2'-C-methyladenosine Chemical Properties
- Boiling point:
- 666.0±65.0 °C(Predicted)
- Density
- 1.68±0.1 g/cm3(Predicted)
- pka
- 13.14±0.70(Predicted)
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N6-Furfuryl-2'-C-methyladenosine Usage And Synthesis
Uses
N6-Furfuryl-2’-C-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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