Basic information Safety Supplier Related

RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT

Basic information Safety Supplier Related

RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Basic information

Product Name:
RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT
Synonyms:
  • Ribavirin 5'-monophosphate (lithium salt)
  • 1-(5-O-Phosphono-β-D-ribofuranosyl)-
  • Ribavirin 5'-Monophosphate DilithiuM Salt (90%)
  • RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT
  • Ribavirin 5'-monophosphate (dilithium)
  • Ribavirin 5'-monophosphate (lithium salt)
  • Ribavirin 5’-Monophosphate Dilithium Salt (90%)
CAS:
66983-94-6
MF:
C17H19Li2N4O9P
MW:
468.21
Product Categories:
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Anti-virals
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Non-nucleoside Reverse Transcriptase
  • Pharmaceuticals
  • Metabolites & Impurities
  • Nucleotides
Mol File:
Mol File
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RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Chemical Properties

Melting point:
220°C dec.
storage temp. 
-20°C Freezer
solubility 
Aqueous Acid (Slightly), Water (Slightly, Sonicated)
form 
Solid
color 
Off-White to Pale Beige
Stability:
Hygroscopic
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RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Usage And Synthesis

Description

Ribavirin 5''-monophosphate inhibits viral DNA and RNA replication in vitro via the strong competitive inhibition of inosine monophosphate dehydrogenase (IMPDH), with a reported Ki value of 270 nM, and thus inhibits guanosine triphosphate synthesis. This agent, a metabolite of the prodrug ribavirin , exhibits broad-spectrum antiviral activity, particularly against myxoviruses. The antiviral effects of ribavirin require conversion to the monophosphate form via adenosine kinase. The anti-HIV activity of ribavirin in cultured human lymphocytes, as well as the anti-influenza activity of this prodrug in MDCK cells, have been attributed to ribavirin 5''-monophosphate.

Chemical Properties

RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT is Solid

Uses

A metabolite of Ribavirin.

Uses

RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT is used as an antiviral agent

RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALTSupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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info@efebio.com
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
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RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT(66983-94-6)Related Product Information