NETROPSIN DIHYDROCHLORIDE HYDRATE
NETROPSIN DIHYDROCHLORIDE HYDRATE Basic information
- Product Name:
- NETROPSIN DIHYDROCHLORIDE HYDRATE
- Synonyms:
-
- 1H-Pyrrole-2-carboxamide, 4-(aminoiminomethyl)aminoacetylamino-N-5-(3-amino-3-iminopropyl)aminocarbonyl-1-methyl-1H-pyrrol-3-yl-1-methyl-, dihydrochloride
- Netropsin hydrate dihydrochloride
- Nsc275885
- Netropsin, 2 HCl, Streptomycesnetropsis (1.24791)
- NETROPSIN DIHYDROCHLORIDE HYDRATE 96%
- netropsin2HClhydrate
- CAS:
- 18133-22-7
- MF:
- C18H27ClN10O3
- MW:
- 466.93
- Mol File:
- 18133-22-7.mol
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NETROPSIN DIHYDROCHLORIDE HYDRATE Chemical Properties
- storage temp.
- 2-8°C
- solubility
- H2O: soluble1mg/mL
- form
- powder
- color
- faint yellow
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NETROPSIN DIHYDROCHLORIDE HYDRATE Usage And Synthesis
Uses
Netropsin Dihydrochloride is DNA minor groove binding ligand.
Biochem/physiol Actions
Netropsin is an unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin disrupts the cell cycle, prolonging G and arresting in G.
NETROPSIN DIHYDROCHLORIDE HYDRATESupplier
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