N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Chemical Properties

Boiling point:

220 °C(lit.)

Density 

0.883 g/mL at 25 °C(lit.)

vapor pressure 

3Pa at 20℃

refractive index 

n20/D 1.4630(lit.)

Flash point:

220 °F

pka

10.32±0.19(Predicted)

Water Solubility 

1000g/L at 25℃

LogP

-0.56 at 25℃

EPA Substance Registry System

1,3-Propanediamine, N'-(3-aminopropyl)-N,N-dimethyl- (10563-29-8)

Safety Information

Hazard Codes 

C

Risk Statements 

21/22-34

Safety Statements 

23-26-36/37/39-45

RIDADR 

UN 2735 8/PG 2

WGK Germany 

1

RTECS 

TX7000000

HazardClass 

8

PackingGroup 

III

Toxicity

LD50 orl-unr: 1432 mg/kg GTPZAB 28(11),50,84

N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Usage And Synthesis

Uses

N,N-Dimethyldipropylenetriamine (DP) may be used to:

• Prepare poly(ethylene oxide)-b-poly(3-caprolactone-g-DP) [PEO-b-P(CL-g-DP)], a biodegradable amphiphilic polycationic copolymer.
• Develop a second generation aminoglycoside 6′-N-acetyltransferase (AAC(6′) inhibitor.
• Prepare a hydrophilic gemcitabine conjugated cationic copolymer, which can be employed in the treatment pancreatic cancer.

General Description

N,N-Dimethyldipropylenetriamine is an aliphatic acyclic amine that is commonly used to develop polymeric system for gene delivery.

Flammability and Explosibility

Non flammable

Safety Profile

A poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.

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