DYNLL1 antibody Usage And Synthesis

Applications

DYNLL1 antibody has been tested by ELISA, Western blot analysis and ICC/IF to assure specificity and reactivity.

Immunogen

Anti-human DYNLL1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human DYNLL1 protein 1-89 amino acids purified from E. coli.

Background

DYNLL1 is a protein that cooperates with NOS1 causing NOS1 inhibition. Binding of DYNLL1 weakens NOS1 (Neuronal nitric oxide synthase) dimer, a conformation needed for activity, and it regulates several biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that demonstrates high expression in testis and moderate expression in brain.

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