UDP-GalNAz.2Na Chemical Properties

storage temp. 

4°C, away from moisture

form 

Solid

color 

White to off-white

UDP-GalNAz.2Na Usage And Synthesis

Biological Activity

UDP-GalNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GalNAc. UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor[1].

References

[1]. Hang HC, et al. Probing glycosyltransferase activities with the Staudinger ligation. J Am Chem Soc. 2004;126(1):6-7. [2]. Bourgeaux V, et al. Two-step enzymatic synthesis of UDP-N-acetylgalactosamine. Bioorg Med Chem Lett. 2005;15(24):5459-5462. [3]. Hang HC, et al. A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation. Proc Natl Acad Sci U S A. 2003;100(25):14846-14851. doi:10.1073/pnas.2335201100 [4]. Lo PW, et al. O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2. Proc Natl Acad Sci U S A. 2018;115(28):7302-7307. [5]. Vanessa Bourgeaux, et al. Two-step enzymatic synthesis of UDP-N-acetylgalactosamine. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5459-62.

UDP-GalNAz.2Na(653600-61-4)Related Product Information

• UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT
• UDP-ALPHA-D-N-ACETYLGALACTOSAMINE, DISODIUM SALT
• Guanosine 5′-diphospho-β-L-fucose
• Uridine 5'-diphosphoglucose disodium salt
• UDP-6-azido-6-deoxy-D-Gal.2Na
• UDP-GlcNTFA.2Na
• Uridine 5'-(trihydrogen diphosphate) P'-(6-azido-6-deoxy-alpha-D-glucopyranosyl) ester
• cytidine monophosphate-N-glycoloylneuraminic acid
• UDP-L-arabinose
• UDP-a-D-Xylose disodium
• URIDINE 5'-DIPHOSPHOGLUCOSE DISODIUM SALT
• UDPGA TRISODIUM SALT
• UDP-GlcNAz.2Na
• UDP-ALPHA-D-GALACTOSE DISODIUM SALT
• Uridine 5'-diphospho-galuronic acid trisodium
• uridine-2-deoxy-2-fluoro-D-glucose diphosphate ester
• UDP-GalNAz
• UDP-GlcNAz