UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT Chemical Properties

storage temp. 

-20°C

solubility 

Methanol (Slightly, Heated), Water (Slightly)

form 

Solid

color 

White to off-White

biological source

bakers yeast

Water Solubility 

water: 50mg/mL

InChIKey

BREKHDYLBRBJNL-ALFVBSQCNA-N

SMILES

O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(=O)C)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,14,16,19,21,23,29,r|

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-26-36

WGK Germany 

3

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT Usage And Synthesis

Chemical Properties

White to off-white crystalline powder

Uses

GlcNAc transferase substrate

Uses

Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) sodium salt has been used:

• as a component of reaction cocktail in endoplasmic reticulum to Golgi transport assay
• as a reference standard for the quantification of UDP-GlcNAc in liver tissues using high-performance liquid chromatography (HPLC)
• in testing the glycosylation activity of O-GlcNAc transferase (OGT) against peptide substrate

Uses

Uridine-5'-diphospho-N-acetylglucosamine sodium salt is used as a chemical reagent in studies relating to the synthesis of immunogens.

General Description

Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). UDP-GlcNAc is transported actively into Golgi, nucleotide sugar transporter (NST). The levels of UDP-GlcNAc is modulated by the concentration of nutrients exposed to the cell.

Biochem/physiol Actions

Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a sugar donor and aids in the endomembrane glycosylation of endoplasmic reticulum and Golgi. The decreased levels of UDP-GlcNAc has an influence on the normal cellular proliferation and apoptosis. UDP-GlcNAc elicits feedback inhibition of the enzyme glutamine:fructose-6-phosphate amidotransferase (GFAT).

UDP-ALPHA-D-N-ACETYLGLUCOSAMINE, DISODIUM SALT(91183-98-1)Related Product Information

• UDP-ALPHA-D-N-ACETYLGALACTOSAMINE, DISODIUM SALT
• UDP-GalNAc disodium salt
• UDP-a-D-Xylose disodium
• URIDINE 5'-DIPHOSPHOGLUCOSE DISODIUM SALT
• UDPGA TRISODIUM SALT
• UDP-GlcNAz.2Na
• UDP-ALPHA-D-GALACTOSE DISODIUM SALT
• UDP-GalNAz.2Na
• Uridine Diphosphate Choline
• [[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy
• 2',2'-DIFLUORO-2'-DEOXYURIDINE
• 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-methylene-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
• Tetrahydrouridine
• 1-(-D-Xylofuranosyl)uracil
• Uridine Diphosphate Choline (UDPC) Sodium Salt
• Uridine 5'-diphospho-galuronic acid trisodium
• 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[(1,1-dimethylethyl)diphenylsilyl]-β-D-ribofuranosyl]-
• [5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid