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Alectinib Impurity 10

Basic information Safety Supplier Related

Alectinib Impurity 10 Basic information

Product Name:
Alectinib Impurity 10
Synonyms:
  • Alectinib Impurity 10
  • 5H-Benzo[b]carbazole-3-carbonitrile, 8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-
  • 8-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
CAS:
1256584-81-2
MF:
C28H29N3O3
MW:
455.55
Mol File:
1256584-81-2.mol
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Alectinib Impurity 10 Chemical Properties

Boiling point:
728.3±60.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
13.70±0.40(Predicted)
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Alectinib Impurity 10 Usage And Synthesis

Uses

8-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile is an intermediate used in the synthesis of Alectinib M4 metabolite (A521150), which is the major active metabolite of Alectinib. Alectinib is an anaplastic lymphoma kinase (ALK) inhibitor and is used to treat non-?small-?cell lung cancer by blocking the activity of anaplastic lymphoma kinase (ALK).

Alectinib Impurity 10Supplier

Guangzhou Dreampharm Biotechnology Co., Ltd.
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020-36607679 17825480238
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Jinan blalong chemical co. LTD
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2710913286@.com
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QUALITY CONTROL SOLUTIONS LTD.
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0755-66853366; 13670046396
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Molcoo Chemicals Inc.
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18627756402
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Shanghai YuZn Pharm. Technology Co.,Ltd.
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15921286451; 15921286451
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2010681527@qq.com