PHORBOL 12,13-DIACETATE
PHORBOL 12,13-DIACETATE Basic information
- Product Name:
- PHORBOL 12,13-DIACETATE
- Synonyms:
-
- Phorbol 12,13-Diacetate >99%
- (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-(hydroxyMethyl)-1,1,6,8-tetraMethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl diacetate
- PHORBOL 12,13-DIACETATE
- PHORBOL 12,13-DIACETATE, 4BETA
- PDA
- 5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-alpha,16-beta,4,4a,7a-alpha,7b,
- 8,9,9a-decahydro-4a-beta,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-(hydroxymethy
- l)-1,1,6,8-alpha-tetramethyl-,9,9a-diacetate,(+)
- CAS:
- 24928-15-2
- MF:
- C24H32O8
- MW:
- 448.51
- Product Categories:
-
- Activator
- Mol File:
- 24928-15-2.mol
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PHORBOL 12,13-DIACETATE Chemical Properties
- Boiling point:
- 477.23°C (rough estimate)
- Density
- 1.1793 (rough estimate)
- refractive index
- 1.4480 (estimate)
- storage temp.
- −20°C
- solubility
- H2O: soluble
- form
- powder
- color
- white
- BRN
- 2317312
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Safety Information
- Hazard Codes
- T+
- Risk Statements
- 26/27/28-36/37/38
- Safety Statements
- 26-27-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- GZ0651000
- F
- 8-10
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 2915290000
MSDS
- Language:English Provider:SigmaAldrich
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PHORBOL 12,13-DIACETATE Usage And Synthesis
Uses
Phorbol 12,13-diacetate may be used to stimulate protein kinase C (PKC) for phosphorylation of retinal proteins.
General Description
Phorbol ester with enhanced hydrophilicity.
Biochem/physiol Actions
Phorbol 12,13-diacetate (PDA) serves as a protein kinase C (PKC). It induces arrest in translocation in rod photoreceptors. PDA facilitates PKC in regulating airway contractility by inducing transient relaxation after a sustained contraction of the human isolated bronchus. PDA improves the synaptic transmission of nociceptive parabrachioamygdaloid (PBA) input onto neurons of the capsular central amygdaloid (CeAC) nucleus via activating PKC and extracellular-regulated kinase (ERK).
PHORBOL 12,13-DIACETATESupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Syntechem Co.,Ltd
- Tel
- info@syntechem.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
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PHORBOL 12,13-DIACETATE(24928-15-2)Related Product Information
- PHORBOL 12-MYRISTATE 13-ACETATE
- ortho-phenylenediamine(o-pda
- POTATO DEXTROSE AGAR (PDA)
- 1,4-Di(acryloyl)piperazine, N,Nμ-Bis(acryloyl)piperazine, BAP, PDA, Piperazine diacrylamide,PDA,PDA, 1,4-Bis(acryloyl)piperazine
- meta-phenylenediamine(m-pda
- para-phenylenediamine(p-pda
- 2-N-p-PDA
- 4-n-o-pd
- 1-PYRENEDECANOIC ACID (PDA)
- PHORBOL
- PHORBOL 12,13-DIACETATE
- PDDHV
- PHORBOL 12,13,20-TRIACETATE, 4BETA
- PHORBOL 12,13-DIDECANOATE
- PHORBOL 12,13-DIBUTYRATE
- 3H-PMA
- PDNHV
- PHORBOL 12-N-METHYLANTHRANILATE