DODAP
DODAP Basic information
- Product Name:
- DODAP
- Synonyms:
-
- 18:1 DAP
- 9-Octadecenoic acid(9Z)-1,1'-[1-[(dimethylamino)methyl]-1,2-ethanediyl] ester
- 1,2-DIOLEOYLOXY-3-(DIMETHYLAMINO)PROPANE
- 1,2-DIOLEOYL-3-DIMETHYLAMMONIUM-PROPANE
- DODAP
- (+/-)-N,N-dimethyl-N-[2,3-bis(9-(Z)-octadecanoyloxy)propyl]amine
- 1,2-dioleoyl-3-dimethylammonium-propane (DODAP)
- (Z)-3-(Dimethylamino)propane-1,2-diyl dioleate
- CAS:
- 127512-29-2
- MF:
- C41H77NO4
- MW:
- 648.05
- Product Categories:
-
- Mixed Fatty Acids
- Fatty Acid Derivatives & Lipids
- Glycerols
- Glycerols, Fatty Acid Derivatives & Lipids
- Mol File:
- 127512-29-2.mol
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DODAP Chemical Properties
- Boiling point:
- 670.1±55.0 °C(Predicted)
- Density
- 0.916±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 8.02±0.28(Predicted)
- color
- Colourless to Light Yellow
- Stability:
- Light Sensitive; Hydroscopic; Store at -15 to -25°C
- InChIKey
- NYDLOCKCVISJKK-WRBBJXAJSA-N
- SMILES
- C(OC(=O)CCCCCCC/C=C\CCCCCCCC)(CN(C)C)COC(=O)CCCCCCC/C=C\CCCCCCCC
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DODAP Usage And Synthesis
Description
DODAP (18:1) is an ionizable cationic lipid with lower cytotoxicity and high transfection efficiency. DODAP is neutral at physiological pH, but acquires a positive charge inside the endosome due to the protonation of free amines when pH is lower than its pKa (<7).
Chemical Properties
Light Yellow Oil
DODAPSupplier
Shochem(Shanghai)Co.,Ltd Gold
- Tel
- +86-021-51783479 +86-13816874662
- info@shochem.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Suzhou Highfine Biotech Co., Ltd
- Tel
- 0512-68311833 13962195826
- wuhao@highfine.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
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DODAP(127512-29-2)Related Product Information
- 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT
- PEG2000-C-DMG
- 1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[3-(2-pyridyldithio)propionate] (sodiuM salt)
- 1-STERAOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT)
- Hexadecanoic acid, 1,1'-[(1S)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
- 1-STEAROYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
- DMG-PEG 2000
- 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE
- DODMA
- DODAP
- N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
- DOTAP MESYLATE