Basic information Safety Supplier Related

8-CHLORO-2'-DEOXYADENOSINE

Basic information Safety Supplier Related

8-CHLORO-2'-DEOXYADENOSINE Basic information

Product Name:
8-CHLORO-2'-DEOXYADENOSINE
Synonyms:
  • 8-CHLORO-2'-DEOXYADENOSINE
  • 8-CL-DADO
  • 8-Chloro-2'-deoxy-D-adenosine
  • Adenosine, 8-chloro-2'-deoxy-
  • 8-Chloro-2’-deoxyadenosine
CAS:
85562-55-6
MF:
C10H12ClN5O3
MW:
285.69
Mol File:
85562-55-6.mol
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8-CHLORO-2'-DEOXYADENOSINE Chemical Properties

Boiling point:
660.0±65.0 °C(Predicted)
Density 
2.03±0.1 g/cm3(Predicted)
pka
13.65±0.60(Predicted)
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8-CHLORO-2'-DEOXYADENOSINE Usage And Synthesis

Uses

8-Chloro-2'-deoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

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