Basic information Safety Supplier Related

BICALUTAMIDE-D4

Basic information Safety Supplier Related

BICALUTAMIDE-D4 Basic information

Product Name:
BICALUTAMIDE-D4
Synonyms:
  • BICALUTAMIDE-D4
  • Casodex-d4
  • ICI-176334-d4
  • N-[4-Cyano-3-trifluoromethyl)phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4
  • (CI-176334-D4
  • Bicalutamide Impurity 17
  • [2H4]-Bicalutamide
CAS:
1185035-71-5
MF:
C18H14F4N2O4S
MW:
430.37
Product Categories:
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Isotope Labelled Compounds
Mol File:
Mol File
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BICALUTAMIDE-D4 Chemical Properties

Melting point:
192-1940C
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated)
form 
Solid
color 
White to Off-White
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BICALUTAMIDE-D4 Usage And Synthesis

Description

Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.

Chemical Properties

BICALUTAMIDE-D4 is White Solid

Uses

BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0

BICALUTAMIDE-D4Supplier

Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Cato Research Chemicals Inc.
Tel
020-81960175
Email
min.he@cato-chem.com
Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
Email
3003392093@qq.com
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Email
3008233746@qq.com