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Triethylenetetramine Dihydrochloride

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Triethylenetetramine Dihydrochloride Basic information

Product Name:
Triethylenetetramine Dihydrochloride
Synonyms:
  • N,N'-BIS(2-AMINOETHYL)-1,2-ETHANEDIAMINE DIHYDROCHLORIDE
  • TRIETHYLENETETRAMINE DIHYDROCHLORIDE
  • TRIENE
  • 2,2’-ethylenediiminobis(ethylamine)dihydrochloride
  • 2-ethanediamine,n,n’-bis(2-aminoethyl)-dihydrochloride
  • mk-0681
  • TriethylenetetraMine Dihydrochloride (Trientine Hydrochloride )
  • 1,2-EthanediaMine,N1,N2-bis(2-aMinoethyl)-, hydrochloride (1:2)
CAS:
38260-01-4
MF:
C6H20Cl2N4
MW:
219.16
EINECS:
253-854-3
Product Categories:
  • TICAR
  • Organic Building Blocks
  • Enzymes
  • Inhibitors
  • Nitrogen Compounds
  • R to Z
  • Superoxide dismutase
  • Amine Salts
  • and Substrates
  • Biochemicals and Reagents
  • Building Blocks
  • Chemical Synthesis
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Enzyme
Mol File:
38260-01-4.mol
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Triethylenetetramine Dihydrochloride Chemical Properties

Melting point:
120-125 °C (dec.)
storage temp. 
2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
BRN 
5961763
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
2
RTECS 
KH8587085
3
HS Code 
2921290055

MSDS

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Triethylenetetramine Dihydrochloride Usage And Synthesis

Description

Trientine hydrochloride is a copper chelating agent recommended for the treatment of Wilson's Disease, especially in patients intolerant of penicillamine therapy. Unlike the latter agent, trientine is not indicated in cystinuria or rheumatoid arthritis.

Chemical Properties

white crystalline powder

Originator

Cambridge University (United Kingdom)

Uses

Triethylenetetramine Hydrochloride is a selective CuII-chelator; crosslinking agent. Triethylenetetramine is undergoing trials for the treatment of heart failure in patients with diabetes.

Uses

antibacterial

Uses

As thermosetting resin; epoxy curing agent; lubricating oil additive; analytical reagent for Cu, Ni.

Definition

ChEBI: Trientine hydrochloride is a secondary amino compound.

brand name

Syprine (Merck);CUPRID.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Trientine Hydrochloride is administered for relief of symptoms of Wilson′s disease for penicillamine intolerance, hence is employed as an oral medication for the treatment of an inherited defect in copper metabolism.

Triethylenetetramine Dihydrochloride Preparation Products And Raw materials

Raw materials

Triethylenetetramine DihydrochlorideSupplier

Energy Chemical
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Sinopharm Chemical Reagent Co,Ltd.
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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Spectrum Chemical Manufacturing Corp.
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