(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Chemical Properties

Boiling point:

464.5±33.0 °C(Predicted)

Density 

0.983±0.06 g/cm3(Predicted)

Flash point:

14 °C

storage temp. 

−20°C

pka

4.78±0.10(Predicted)

form 

Liquid (Density: 0.983±0.06 g/cm3)

color 

Colorless to light yellow

Safety Information

Hazard Codes 

F,Xi

Risk Statements 

11-36/37/38

Safety Statements 

16-26-36-7

RIDADR 

UN 1170 3/PG 2

(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Usage And Synthesis

Uses

Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,?N''-?dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore.Also, it is derived from Arachidonic Acid >97% (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.

Definition

ChEBI: 14,15-Epoxy-5,8,11-eicosatrienoic acid is a long-chain fatty acid.

in vivo

IC 50

Human Endogenous Metabolite

(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID(81276-03-1)Related Product Information

• (+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
• (+/-)-CIS-14,15-EPOXY-5(Z),8(Z),11(Z)-EICOSATRIENOIC ACID
• 14(S),15(R)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
• (+/-)14(15)-EPETRE METHYL ESTER
• 2-(14,15-EPOXYEICOSATRIENOYL) GLYCEROL
• METHYL-14(S),15(S)-EPOXY-13(R)-HYDROXY-5(Z),8(Z),11(Z)-EICOSATRIENOATE
• 14(R),15(S)-EPOXY-(5Z,8Z,11Z)-EICOSATRIENOIC ACID
• METHYL 13(S)-HYDROXY-14(S),15(S)-EPOXY-5(Z),8(Z),11(Z)-EICOSATRIENOATE
• METHYL 13(R)-HYDROXY-14(S),15(S)-EPOXY-5(Z),8(Z),11(Z)-EICOSATRIENOATE
• METHYL-14(S),15(S)-EPOXY-13(S)-HYDROXY-5(Z),8(Z),11(Z)-EICOSATRIENOATE