4-HYDROXY-4-PHENYLPIPERIDINE Chemical Properties

Melting point:

157-161 °C(lit.)

Boiling point:

317.9±42.0 °C(Predicted)

Density 

1.093

storage temp. 

2-8°C(protect from light)

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

14.13±0.20(Predicted)

color 

Pale brown

BRN 

141577

InChIKey

KQKFQBTWXOGINC-UHFFFAOYSA-N

CAS DataBase Reference

40807-61-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2933399990

MSDS

• Language:English Provider:SigmaAldrich

4-HYDROXY-4-PHENYLPIPERIDINE Usage And Synthesis

Uses

Reactant for synthesis of:

• Diaminotriazine hNav1.7 inhibitors
• Selective σ?ligands
• Glycogen synthase kinase-3β?inhibitors
• Diphenylbutylpiperidines as cell autophagy inducers
• Malonyl-coA decarboxylase inhibitors with antiobesity and antidiabetic activities
• Selective dopamine D2 receptor antagonists

Synthesis Reference(s)

Journal of the American Chemical Society, 78, p. 1702, 1956 DOI: 10.1021/ja01589a060

4-HYDROXY-4-PHENYLPIPERIDINE(40807-61-2)Related Product Information

• 4-(4-Bromophenyl)-4-piperidinol
• 4-(4-Chlorophenyl)piperidin-4-ol
• Haloperidol
• 4-(3-Trifuoromethyl)phenyl-4-piperidinol
• alphaprodine
• 4-[3-(TRIFLUOROMETHYL)PHENYL]-4-PIPERIDINOL HYDROCHLORIDE
• 4-HYDROXY-4-PHENYLPIPERIDINE
• Loperamide hydrochloride
• 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
• Ethyl 4-(4-chloro-3-(trifluoromethyl)phenyl)-4-hydroxypiperidine-1-carboxylate
• 4-Hydroxypiperidine
• 4-Phenylpiperidine
• (4-hydroxy-1-methyl-4-phenyl-3-piperidyl)-phenyl-methanone
• 4-(4-FLUORO-PHENYL)-PIPERIDIN-4-OL HYDROCHLORIDE
• 1-methyl-4-phenylpiperidin-4-ol
• TRIFLUPERIDOL HCL
• HALOPERIDOL METABOLITE II
• 4-[4-(4-CHLOROPHENYL)-4HYDROXY-1-PIPERIDINYL]-1-(4-CHLOROPHENYL)-1-BUTANONE