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4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line

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4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line Basic information

Product Name:
4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line
Synonyms:
  • 4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line
  • Oxazole, 4,5-dihydro-4,4-dimethyl-2-(1-methyl-1-phenylethyl)-
  • 4,4-dimethyl-2-(2-phenylpropan-2-yl)-4,5-dihydrooxazole
  • Bilastine impurity 08
CAS:
874895-87-1
MF:
C14H19NO
MW:
217.31
Mol File:
874895-87-1.mol
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4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line Chemical Properties

Boiling point:
292.0±19.0 °C(Predicted)
Density 
0.99±0.1 g/cm3(Predicted)
solubility 
soluble in Dichloromethane
form 
Oil
pka
5.79±0.70(Predicted)
color 
Yellow
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4,4-dimethyl-2-(2-phenylpropan-2-yl)oxazo‐ line Usage And Synthesis

Uses

4,5-Dihydro-4,4-dimethyl-2-(1-methyl-1-phenylethyl)oxazole-d6 is an intermediate used in the synthesis of Bilastine-d6 (B385002), which is labelled Bilastine. It is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.

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