4-Nitroindanone Chemical Properties

Melting point:

104-105 °C

Boiling point:

332.9±31.0 °C(Predicted)

Density 

1.396±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

InChI

InChI=1S/C9H7NO3/c11-9-5-4-6-7(9)2-1-3-8(6)10(12)13/h1-3H,4-5H2

InChIKey

QIIWEVWPOBNGLP-UHFFFAOYSA-N

SMILES

C1(=O)C2=C(C([N+]([O-])=O)=CC=C2)CC1

Safety Information

HazardClass 

IRRITANT

HS Code 

2914790090

4-Nitroindanone Usage And Synthesis

Description

4-Nitroindanone (4-Nitro-1-indanone) is an important chemical reagent used as a raw material in organic synthesis for the preparation of other cyclic compounds. In biology, it can inhibit the cysteine protease thioredoxin reductase and also interacts with cardiac potassium channels and is cytotoxic to human erythrocytes. In a rat model of atrial fibrillation, 4-nitro-1-indanone was found to have antiarrhythmic properties.

Uses

4-Nitroindanone is a versatile building block, capable of undergoing microwave-assisted oxidation to form ninhydrins. 4-Nitroindanone also has pharmaceutical relevance, as its thiosemicarbazone derivative has anti-Trypanosoma cruzi properties.

4-Nitroindanone(24623-25-4)Related Product Information

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