DSLET
DSLET Basic information
- Product Name:
- DSLET
- Synonyms:
-
- (D-SER2)-LEU-ENKEPHALIN-THR
- (D-SER2)-LEU-ENKEPHALIN-THR-OH
- DSLET
- DELTA-RECEPTOR PEPTIDE
- tyrosyl-seryl-glycyl-phenylalanyl-leucyl-threonine
- (D-ser2)-leucine enkephalin-thr acetate
- (D-SER2)-LEUCINE ENKEPHALIN-THR
- (D-serine2)leucine enkephalin threonine acetate
- CAS:
- 75644-90-5
- MF:
- C33H46N6O10
- MW:
- 686.75
- Product Categories:
-
- Opioid receptor and opioid-like receptor
- Mol File:
- 75644-90-5.mol
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DSLET Chemical Properties
- storage temp.
- -15°C
- solubility
- Soluble to 0.50 mg/ml in sterile water
- form
- Powder
- Sequence
- Tyr-L-Ser-Gly-Phe-Leu-Thr
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DSLET Usage And Synthesis
Uses
DSLET ([D-Ser2, Leu5, Thr6]-enkephalin) is a highly specific agonist of the δ-receptor. DSLET is an enkephalin-related peptide selectively bound to the δ opioid receptor[1][2].
Definition
ChEBI: DSLET is an oligopeptide.
IC 50
δ Opioid Receptor/DOR
References
[1] J L Nano, et al. Characterization of delta-opioid receptors and effect of enkephalins on IRD 98 rat epithelial intestinal cell line. Pflugers Arch. 2000 Mar;439(5):547-54. DOI:10.1007/s004249900160
[2] C S Goodchild, et al. Antinociception by intrathecal midazolam involves endogenous neurotransmitters acting at spinal cord delta opioid receptors. Br J Anaesth. 1996 Dec;77(6):758-63. DOI:10.1093/bja/77.6.758
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