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4-Methylamino-3-nitro-benzonitrile

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4-Methylamino-3-nitro-benzonitrile Basic information

Product Name:
4-Methylamino-3-nitro-benzonitrile
Synonyms:
  • 4-Methylamino-3-nitro-benzonitrile
  • Benzonitrile, 4-(methylamino)-3-nitro-
CAS:
64910-45-8
MF:
C8H7N3O2
MW:
177.16
Mol File:
Mol File
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Safety Information

HS Code 
2926907090
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4-Methylamino-3-nitro-benzonitrile Usage And Synthesis

Uses

4-(Methylamino)-3-nitrobenzonitrile

Synthesis

A solution of 4-chloro-3-nitrobenzonitrile and methylamine was mixed and stirred in tetrahydrofuran, then concentrated and suspended in diethyl ether for filtration to obtain the crude product 4-methylamino-3-nitro-benzonitrile.

References

[1] Tran, G., Confair, D., Hesp, K. D., Mascitti, V., & Ellman*, J. A. (2017). C2-Selective Branched Alkylation of Benzimidazoles by Rhodium(I)-Catalyzed C–H Activation. Journal of Organic Chemistry, 82 17, 9243–9252. https://doi.org/10.1021/acs.joc.7b01723

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