Basic information Safety Supplier Related

2-(4-Methoxyphenyl)-2-oxoethyl acetate

Basic information Safety Supplier Related

2-(4-Methoxyphenyl)-2-oxoethyl acetate Basic information

Product Name:
2-(4-Methoxyphenyl)-2-oxoethyl acetate
Synonyms:
  • 2-(4-Methoxyphenyl)-2-oxoethyl acetate
  • Ethanone, 2-(acetyloxy)-1-(4-methoxyphenyl)-
CAS:
58518-78-8
MF:
C11H12O4
MW:
208.21058
Mol File:
58518-78-8.mol
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2-(4-Methoxyphenyl)-2-oxoethyl acetate Chemical Properties

Melting point:
63-65°
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Safety Information

HazardClass 
IRRITANT
HS Code 
2918999090
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2-(4-Methoxyphenyl)-2-oxoethyl acetate Usage And Synthesis

Preparation

Obtained by reaction of sodium acetate with 2-bromo-4′-methoxyacetophenone in boiling methanol for 48 h (43%)
Also obtained by reaction of potassium thioacetate with 4-methoxy-a-chloroacetophenone
Also obtained from 4-methoxyacetophenone and [hydroxy(tosyloxy)iodo]ben-zene (HTIB)/polymer-supported [hydroxy(tosyloxy)iodo]benzene (PSHTIB) in N,N-dimethyl-formamide/dimethylacetamide (74%).

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 25, p. 973, 1988 DOI: 10.1002/jhet.5570250351

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