4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)
4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide) Basic information
- Product Name:
- 4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)
- Synonyms:
-
- 4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)
- 2,5-bis(4-amidinophenyl)furan
- 2,5-Bis(4-guanylphenyl)furan
- NSC 305831
- 2,5-Bis(4-aMidinophenyl)furan-d8
- 2,5-Bis(4-guanylphenyl)furan-d8
- FuraMidine-d8
- NSC 305831-d8
- CAS:
- 73819-26-8
- MF:
- C18H16N4O
- MW:
- 304.35
- Mol File:
- 73819-26-8.mol
More
Less
4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide) Usage And Synthesis
Uses
Labelled analogue of Furamidine, a diphenylfuran compound belonging to an important class of antimicrobial and antiparasitic agents. Furamidine and its analogues also display antitumor activities and showed antiproliferative activities against various tumor cell lines.
in vivo
Furamidine (1 mg/kg; intraperitoneal injection; 3 times a week and repeated every 4 weeks; for 34 weeks; female NZB/NZW mice) and Irinotecan combined treatment suppresses proteinuria and prolongs survival of lupus-prone NZB/NZW mice. The combination treatment does not change the levels of anti-dsDNA antibodies[3].
| Animal Model: | Female NZB/NZW mice (6-week-old) with Irinotecan (1 mg/kg)[3] |
| Dosage: | 1 mg/kg |
| Administration: | Intraperitoneal injection; 3 times a week and repeated every 4 weeks; for 34 weeks |
| Result: | Suppressed proteinuria and prolongs survival of lupus-prone NZB/NZW mice combined with Irinotecan. |
4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)Supplier
Chemsky (shanghai) International Co.,Ltd
- Tel
- 021-50135380
- shchemsky@sina.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
Energy Chemical
- Tel
- 021-58432009 400-005-6266
- marketing@energy-chemical.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com