FARNESYLTHIOACETIC ACID Chemical Properties

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

form 

Yellow viscous oil.

Sensitive 

Light Sensitive

FARNESYLTHIOACETIC ACID Usage And Synthesis

Description

S-Farnesyl thioacetic acid is an analog of S-farnesyl cysteine which behaves as a competitive inhibitor of isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). It can also inhibit methylation of both farnesylated and geranylgeranylated substrates.

Uses

S-Farnesyl thioacetic acid is an analog of S-farnesyl cysteine, which is a prenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase) competitive inhibitors. It also inhibits the methylation of farnesylated and geranylgeranylated substrates.

Definition

ChEBI: 2-(3,7,11-trimethyldodeca-2,6,10-trienylthio)acetic acid is a sesquiterpenoid.

References

[1] RANDO R R. Chemical biology of protein isoprenylation/methylation[J]. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996, 1300 1: Pages 5-16. DOI: 10.1016/0005-2760(95)00233-2

FARNESYLTHIOACETIC ACID(135784-48-4)Related Product Information

• SINEFUNGIN
• AFC
• Chaetocin
• Thioacetic acid
• ALLYLSULFANYL-ACETIC ACID
• (E)-3,7-Dimethylocta-2,6-diene-1-thiol
• FARNESYLTHIOACETIC ACID