Basic information Safety Supplier Related

ML 236A

Basic information Safety Supplier Related

ML 236A Basic information

Product Name:
ML 236A
Synonyms:
  • ML 236A
  • (4R)-4α-Hydroxy-6β-[2-[(1S)-2β-methyl-8α-hydroxy-1,2,6,7,8,8aβ-hexahydronaphthalene-1β-yl]ethyl]tetrahydro-2H-pyran-2-one
  • (4R)-6β-[2-[(1S)-1,2,6,7,8,8aβ-Hexahydro-8α-hydroxy-2β-methylnaphthalene-1β-yl]ethyl]tetrahydro-4α-hydroxy-2H-pyran-2-one
  • 6β-[2-[[(1S)-1,2,6,7,8,8aβ-Hexahydro-8α-hydroxy-2β-methylnaphthalen]-1β-yl]ethyl]tetrahydro-4α-hydroxy-2H-pyran-2-one
  • DesmethylmonacolinJ
  • Compactin diol lactone
  • 2H-Pyran-2-one, 6-[2-[(1S,2S,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2-methyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-, (4R,6R)-
CAS:
58889-19-3
MF:
C18H26O4
MW:
306.399
Mol File:
58889-19-3.mol
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ML 236A Chemical Properties

Melting point:
126-132 °C
Boiling point:
535.2±50.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
pka
13.49±0.40(Predicted)
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ML 236A Usage And Synthesis

Definition

ChEBI: Compactin diol lactone is a carbobicyclic compound that is ML-236C substituted by a hydroxy group at position 8S. It is a fungal metabolite isolated from Penicillium citrinum and exhibits anticholesteremic activity. It has a role as a fungal metabolite, an EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor, an antilipemic drug, an antiatherosclerotic agent, an anticholesteremic drug and an antimicrobial agent. It is a carbobicyclic compound, a member of 2-pyranones, a member of hexahydronaphthalenes, a secondary alcohol and a polyketide. It is functionally related to a ML-236C.

ML 236ASupplier

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