JG 365
JG 365 Basic information
- Product Name:
- JG 365
- Synonyms:
-
- JG 365
- Ac-L-Ser-L-Leu-L-Asn-L-Pheψ[CH(OH)CH2N]-L-Pro-L-Ile-L-Val-OMe
- N-[(3S)-2-Hydroxy-3-[(Ac-L-Ser-L-Leu-L-Asn-)amino]-4-phenylbutyl]-L-Pro-L-Ile-L-Val-OMe
- N-Acetyl-L-Ser-L-Leu-L-Asn-[(3S)-3-benzyl-2-hydroxy-1-deoxo-βAla-]-L-Pro-L-Ile-L-Val-OMe
- L-Valine, 1-[3-[(N-acetyl-L-seryl-L-leucyl-L-asparaginyl)amino]-2-hydroxy-4-phenylbutyl]-L-prolyl-L-isoleucyl-, methyl ester
- CAS:
- 132748-20-0
- MF:
- C42H68N8O11
- MW:
- 861.04
- Mol File:
- 132748-20-0.mol
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JG 365 Chemical Properties
- Boiling point:
- 1216.5±65.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- pka
- 13.18±0.46(Predicted)
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JG 365 Usage And Synthesis
Uses
JG-365 is an HIV-1 protease inhibitor that binds to the active site of HIV-1 protease.
References
[1] Insights from atomic-resolution X-ray structures of chemically synthesized HIV-1 protease in complex with inhibitors DOI:10.1016/j.jmb.2007.07.054