ANTI-BAX Antibody
ANTI-BAX Antibody Basic information
- Product Name:
- ANTI-BAX Antibody
- Synonyms:
-
- MONOCLONAL ANTIBODY TO BAX (2D2), HUMAN
- MONOCLONAL ANTIBODY TO BAX (6A7), UNIVERSAL
- Monoclonal Anti-Bax antibody produced in mouse
- BAX (AB-1) POLYCLONAL ANTIBODY
- BAX (AB-2) MONOCLONAL ANTIBODY
- BAX (AB-3) MONOCLONAL ANTIBODY
- BAX (AB-4) POLYCLONAL ANTIBODY
- BAX (AB-5) MONOCLONAL ANTIBODY
- MW:
- 0
- Product Categories:
-
- OncoproteinsAntibodies
- 2
- Alphabetical Index
- Antibodies for Apoptosis
- Apoptosis and Cell Cycle
- Cell Biology
- Antibodies to Bcl-2 Family ProteinsAntibodies
- BCell Signaling and Neuroscience
- Bcl-2 Family ProteinsCancer Research
- Clone Index
- Tumor Growth Regulation
- 6
- 5
- Mol File:
- Mol File
ANTI-BAX Antibody Chemical Properties
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
MSDS
- Language:English Provider:SigmaAldrich
ANTI-BAX Antibody Usage And Synthesis
Uses
Monoclonal Anti-Bax antibody is suitable for use in western blot (1-5 μg/mL using cultured human breast adenocarcinoma MCF-7 cells, activated with dexamethasone) and microarray.
General Description
Bax is a tumor suppressor that belongs to the Bcl-2 family and modulates cellular apoptosis. Bax is regulated by p53 and increased Bax levels have been associated with cell death stimuli. Alterations in Bax have been linked to several neurological diseases and cancers . Monoclonal Anti-Bax antibody is specific for the epitope within amino acids 3-16 of the human Bax protein. The antibody reacts with Bax in bovines and humans, but not in mice and rats.
Biological Activity
B-cell lymphoma 2 associated X (BAX) promotes cell death and plays a vital role in regulation of apoptosis. BAX gene may act as a negative regulator of autophagy in CRC (colorectal cancer) development.
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