hypeptin
hypeptin Basic information
- Product Name:
- hypeptin
- Synonyms:
-
- hypeptin
- L-Isoleucine, L-alanyl-D-leucyl-D-arginyl-(3R)-3-hydroxy-L-asparaginyl-(3R)-3-hydroxy-D-asparaginyl-(βS)-β-hydroxy-L-tyrosyl-(3R)-3-hydroxy-L-leucyl-, (8→5)-lactone
- CAS:
- 124883-38-1
- MF:
- C44H71N13O15
- MW:
- 1022.11
- Mol File:
- 124883-38-1.mol
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hypeptin Chemical Properties
- Sequence
- Ala-{d-Leu}-{d-Arg}-Asn-{d-Asn}-Tyr-Leu-Ile (Lactone bridge:Asn5-Ile8)
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hypeptin Usage And Synthesis
Uses
Hypeptin is a cyclo-deposited peptide antibiotic produced by Lysobacter sp.K5869. Hypeptin blocks bacterial cell wall biosynthesis by binding to multiple undecaprenyl pyrophosphate-containing biosynthesis intermediates，forming a stoichiometric 2:1 complex. Hypeptin has antibacterial activity[1].
References
[1] Wirtz DA, et al. Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13579-13586. DOI:10.1002/anie.202102224
hypeptinSupplier
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Zhejiang Huida Biotech Co., LTD
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