2-iodoestradiol Usage And Synthesis

Uses

2-Iodoestradiol is a potent human sex hormone binding globulin (SHBG) ligand with a remarkably high affinity for SHBG. 2-Iodoestradiol exhibits competition for the same binding site as dihydrotestosterone in binding to human SHBG. The binding affinity constant of 2-Iodoestradiol at physiological pH and 37 degrees Celsius is 2.4 x 10(9) M-1, exceeding that for SHBG. 2-Iodoestradiol has been shown to bind to serum albumin, but with lower affinity. The radioisotope 125I-derivative of 2-Iodoestradiol has been used to study the binding properties of human SHBG, demonstrating its potential application in biological research[1].

References

[1] 2-Iodoestradiol binds with high affinity to human sex hormone binding globulin (SHBG)

2-iodoestradiol(24381-12-2)Related Product Information

• 1-N-HEXYL-4-IODOBENZENE
• 4,5-DIMETHYL-2-IODOPHENOL
• 2-iodoestradiol
• 1-N-HEPTYL-4-IODOBENZENE