LACTAMIDE Chemical Properties

Melting point:

73-76 °C(lit.)

Boiling point:

165.17°C (rough estimate)

Density 

1.1948 (rough estimate)

refractive index 

1.4368 (estimate)

pka

13.34±0.20(Predicted)

form 

powder to crystal

color 

White to Almost white

Water Solubility 

782.20g/L(25 ºC)

LogP

-1.161 (est)

CAS DataBase Reference

2043-43-8(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

2924.19.8000

MSDS

• Language:English Provider:SigmaAldrich

LACTAMIDE Usage And Synthesis

Uses

Lactamide is used as a synthetic raw material in organic chemistry, as an additive in cosmetics, and as a preservative in frozen semen and fertilized eggs in livestock reproduction studies.

Definition

ChEBI:Lactamide is a monocarboxylic acid amide that is lactic acid in which the carboxylic acid group has been converted to the corresponding carboxamide. It is a monocarboxylic acid amide and a secondary alcohol. It is functionally related to a rac-lactic acid.

Synthesis

α-Hydroxy methyl ester (10 mmol, 1.0 equiv) was added into the 100 ml RBF, anda saturated methanol solution of ammonia (20 ml, 38 equiv) was added underthe ice-water bath and stirred overnight. The mixture was concentrated underreduced pressure and in most case Lactamide were obtained in high yields,while in rare occasions purified by flash chromatography.

LACTAMIDE(2043-43-8)Related Product Information

• CYTOCHALASIN A
• DIHYDROCYTOCHALASIN B
• Panthenol
• Calcium D-Pantothenate
• VALINOMYCIN
• D-PANTOTHENIC ACID
• LACTAMIDE
• CYTOCHALASIN E
• Sodium D-pantothenate
• 3-hydroxypiperidin-2-one
• 5,5-Dimethyloxazolidine-2,4-dione
• D-GLUCURONAMIDE
• N,N'-DIALLYL-L-TARTARDIAMIDE
• HYDROXYETHYL LACTAMIDE,N-(2-HYDROXYETHYL)LACTAMIDE,Lactamide MEA,Lactamide, N-(2-hydroxyethyl)-,N-(beta-Hydroxyethyl)lactamide,Lactamide monoethanolamine
• 2-HYDROXYISOBUTYRAMIDE(2-METHYL-2-HYDROXYPROPIONAMIDE,METHYL LACTAMIDE)
• (R)-(+)-LACTAMIDE,R-(+)-Lactamide 97+% cp 98+% ee,D-Lactamide
• DL-Lactic acid
• Lactic acid