3'-(O-METHYL)CYTIDINE
3'-(O-METHYL)CYTIDINE Basic information
- Product Name:
- 3'-(O-METHYL)CYTIDINE
- Synonyms:
-
- 3'-(O-METHYL)CYTIDINE
- Cytidine, 3'-O-methyl-
- 3'-(O-METHYL)CYTIDINE USP/EP/BP
- 4-amino-1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]pyrimidin-2-one
- 3'-OMe-Cytidine
- 4-amino-1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one
- CAS:
- 20594-00-7
- MF:
- C10H15N3O5
- MW:
- 257.24
- Product Categories:
-
- Modified（deoxy）nucleoside
- Nucleosides-3'-OMe Nucleosides
- Mol File:
- 20594-00-7.mol
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3'-(O-METHYL)CYTIDINE Chemical Properties
- Boiling point:
- 506.0±60.0 °C(Predicted)
- Density
- 1.68±0.1 g/cm3(Predicted)
- pka
- 13.34±0.70(Predicted)
- form
- Solid
- color
- White to off-white
- InChI
- InChI=1S/C10H15N3O5/c1-17-8-5(4-14)18-9(7(8)15)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
- InChIKey
- RZJCFLSPBDUNDH-ZOQUXTDFSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](O)[C@@H]1OC
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3'-(O-METHYL)CYTIDINE Usage And Synthesis
Uses
3′-O-Methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Definition
ChEBI: 3'-O-Methylcytidine is a pyrimidine nucleoside.
References
[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308
3'-(O-METHYL)CYTIDINESupplier
Fuyang Ziyi Biological Pharmaceutical Co., Ltd. Gold
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