SUC-ALA-PHE-LYS-AMC Chemical Properties

Boiling point:

1039.6±65.0 °C(Predicted)

Density 

1.302±0.06 g/cm3(Predicted)

form 

Solid

pka

4.69±0.10(Predicted)

color 

White to off-white

Sequence

{Suc-Ala}-Phe-{Lys-AMC}

SUC-ALA-PHE-LYS-AMC Usage And Synthesis

Uses

Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K[1][2].

References

[1] P A Pierzchala, et al. A new fluorogenic substrate for plasmin. Biochem J. 1979 Dec 1;183(3):555-9. DOI:10.1042/bj1830555
[2] Marion G G?tz, et al. Aza-peptidyl Michael Acceptors. A New Class of Potent and Selective Inhibitors of Asparaginyl Endopeptidases (Legumains) from Evolutionarily Diverse Pathogens. J Med Chem. 2008 May 8;51(9):2816-32. DOI:10.1021/jm701311r

SUC-ALA-PHE-LYS-AMC(73207-91-7)Related Product Information

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