SUC-ALA-GLU-PRO-PHE-PNA
SUC-ALA-GLU-PRO-PHE-PNA Basic information
- Product Name:
- SUC-ALA-GLU-PRO-PHE-PNA
- Synonyms:
-
- SUC-ALA-GLU-PRO-PHE-PNA
- Suc-AEPF-pNA
- Suc-Ala-Glu-Pro-Phe-pNA≥ 98% (HPLC)
- L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)-
- N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)-L-phenylalaninamide
- Peptidyl-Prolyl Isomerase SubstratesSuc-Ala-Glu-Pr
- (S)-4-((S)-2-(3-Carboxypropanamido)propanamido)-5-((S)-2-(((S)-1-((4-nitrophenyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)pyrrolidin-1-yl)-5-oxopentanoic acid
- CAS:
- 128802-76-6
- MF:
- C32H38N6O11
- MW:
- 682.68
- Product Categories:
-
- ADC Linker
- Mol File:
- Mol File
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SUC-ALA-GLU-PRO-PHE-PNA Chemical Properties
- storage temp.
- -15°C
- form
- Solid
- color
- White to off-white
- Sequence
- {Suc}-Ala-Glu-Pro-Phe-{pNA}
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SUC-ALA-GLU-PRO-PHE-PNA Usage And Synthesis
Chemical Properties
White powder
Uses
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc[1][2].
References
[1] Subedi A, et al. Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening. Biochem Biophys Res Commun. 2016 Jun 3;474(3):528-533. DOI:10.1016/j.bbrc.2016.04.124
[2] Liu C, et al. Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1. Mol Med Rep. 2017 May;15(5):3210-3214. DOI:10.3892/mmr.2017.6399
SUC-ALA-GLU-PRO-PHE-PNASupplier
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Bide Pharmatech Ltd.
- Tel
- 400-164-7117 13681763483
- product02@bidepharm.com
Shanghai Chaolan Chemical Technology Center
- Tel
- 021-QQ：65489617 15618227136
- Sales@ATKchemical.com
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