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PD 117519

Basic information Safety Supplier Related

PD 117519 Basic information

Product Name:
PD 117519
Synonyms:
  • (R)-N-(2,3-Dihydro-1H-indenyl)adenosine
  • N-[(1R)-Indan-1-yl]adenosine
  • N-[[(R)-2,3-Dihydro-1H-inden]-1α-yl]adenosine
  • CI 947
  • N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine
  • PD 117519
  • N-[(R)-Indan-1-yl]adenosine
  • Adenosine, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-
CAS:
96392-15-3
MF:
C19H21N5O4
MW:
383.4
Product Categories:
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
Mol File:
96392-15-3.mol
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PD 117519 Chemical Properties

storage temp. 
2-8°C
solubility 
DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 5mg/mL; Ethanol: 0.1mg/mL
form 
A solid
color 
White to off-white
InChIKey
FSKMJUWPFLDDRS-BYMDKACISA-N
SMILES
OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N[C@H]3C4=C(C=CC=C4)CC3)N=C2)[C@H](O)[C@@H]1O
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PD 117519 Usage And Synthesis

Uses

N6-Substituted adenosine receptor agonist; a potential antihypertensive agent.

in vitro

PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing.

PD 117519Supplier

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