PD 117519
PD 117519 Basic information
- Product Name:
- PD 117519
- Synonyms:
-
- (R)-N-(2,3-Dihydro-1H-indenyl)adenosine
- N-[(1R)-Indan-1-yl]adenosine
- N-[[(R)-2,3-Dihydro-1H-inden]-1α-yl]adenosine
- CI 947
- N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine
- PD 117519
- N-[(R)-Indan-1-yl]adenosine
- Adenosine, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-
- CAS:
- 96392-15-3
- MF:
- C19H21N5O4
- MW:
- 383.4
- Product Categories:
-
- Bases & Related Reagents
- Carbohydrates & Derivatives
- Intermediates & Fine Chemicals
- Nucleotides
- Pharmaceuticals
- Mol File:
- 96392-15-3.mol
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PD 117519 Chemical Properties
- storage temp.
- 2-8°C
- solubility
- DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 5mg/mL; Ethanol: 0.1mg/mL
- form
- A solid
- InChIKey
- FSKMJUWPFLDDRS-BYMDKACISA-N
- SMILES
- OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N[C@H]3C4=C(C=CC=C4)CC3)N=C2)[C@H](O)[C@@H]1O
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PD 117519 Usage And Synthesis
Uses
N6-Substituted adenosine receptor agonist; a potential antihypertensive agent.
in vitro
PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing.
PD 117519Supplier
Zhengzhou Granlen Sciences, ltd. Gold
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- 0371-85513397
- info@granlen.com
J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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Chemsky (shanghai) International Co.,Ltd
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- 021-50135380
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T&W GROUP
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- 021-61551611 13296011611
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Hangzhou Sage Chemical Co., Ltd.
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- +86057186818502 13588463833
- info@sagechem.com