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BOC-8-AMINOCAPRYLIC ACID

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BOC-8-AMINOCAPRYLIC ACID Basic information

Product Name:
BOC-8-AMINOCAPRYLIC ACID
Synonyms:
  • RARECHEM EM WB 0025
  • T-BUTOXYCARBONYL-8-AMINOCAPRYLIC ACID
  • T-BUTOXYCARBONYL-8-AMINOOCTANOIC ACID
  • N-TERT-BUTYLOXYCARBONYL-8-AMINO-OCTANOIC ACID
  • 8-(BOC-AMINO)CAPRYLIC ACID
  • 8-(BOC-AMINO)OCTANOIC ACID
  • BOC-NH-(CH2)7-COOH
  • BOC-AMINOCAPRYLIC ACID
CAS:
30100-16-4
MF:
C13H25NO4
MW:
259.34
Product Categories:
  • Amino Acids
Mol File:
30100-16-4.mol
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BOC-8-AMINOCAPRYLIC ACID Chemical Properties

Melting point:
56-59 °C
Boiling point:
406.0±28.0 °C(Predicted)
Density 
1.036±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
4.78±0.10(Predicted)
BRN 
2268966
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Safety Information

WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29241990

MSDS

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BOC-8-AMINOCAPRYLIC ACID Usage And Synthesis

Description

Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

White amorphous powder

Uses

Reagent to introduce a protected w-amino alkyl spacer. Longer spacer arms often impart increased activity to the substrate

BOC-8-AMINOCAPRYLIC ACIDSupplier

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