Basic information Safety Supplier Related

CAFESTOL

Basic information Safety Supplier Related

CAFESTOL Basic information

Product Name:
CAFESTOL
Synonyms:
  • CAFESTEROL
  • CAFESTOL
  • 3bα,4,5,6,7,8,9,10,10aα,10b,11,12-Dodecahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7α-methanol
  • 5A,8-Methano-5ah-cyclohepta(5,6)naphtho(2,1-B)furan-7-methanol, 3B,4,5,6,7,8,9,10,10A,10B,11,12-dodecahydro-7-hydroxy-10B-methyl-, (3bs-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta))-
  • 5A,8-Methano-5ah-cyclohepta(5,6)naphtho(2,1-B)furan-7-methanol, 3B,4,5,6,7,8,9,10,10A,10B,11,12-dodecahydro-7-hydroxy-10B-methyl-, (3bs,5as,7R,8R,10ar,10bs)-
  • Ccris 1518
  • CAFESTOL(SH)
  • (3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
CAS:
469-83-0
MF:
C20H28O3
MW:
316.43
Product Categories:
  • Di-Terpenoids
Mol File:
469-83-0.mol
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CAFESTOL Chemical Properties

Melting point:
160-162℃ (Decomposition) (ethyl ether pentane )
alpha 
D -101°
Boiling point:
468.6±45.0 °C(Predicted)
Density 
1.23±0.1 g/cm3 (20 ºC 760 Torr)
RTECS 
PB9185090
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Soluble in dichlormethane, DMSO or ethanol
pka
14.44±0.40(Predicted)
form 
White to off-white solid.
color 
Off-White to Light Beige
LogP
4.234 (est)
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CAFESTOL Usage And Synthesis

Uses

Natural extract from coffee beans which induces glutathione S-transferase

Uses

Cafestol is a diterpene molecule that displays anti-carcinogenic properties in studies.

Definition

ChEBI: Cafestol is an organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). It has a role as a plant metabolite, an apoptosis inducer, a hypoglycemic agent, an angiogenesis inhibitor, an antineoplastic agent, an antioxidant and an anti-inflammatory agent. It is an organic heteropentacyclic compound, a tertiary alcohol, a diterpenoid, a member of furans and a primary alcohol.

CAFESTOLSupplier

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